Orphenadrine
http://dbpedia.org/resource/Orphenadrine an entity of type: Thing
(Orphenadrine) مناهض مسكاريني
rdf:langString
Orphenadrin ist ein zentral wirksamer Arzneistoff, der die Skelettmuskulatur entspannt und damit zu den Muskelrelaxanzien zählt. Orphenadrin gehört zur Klasse der H1-Antihistaminika und ist chemisch verwandt mit Diphenhydramin. Es wird angewendet zur symptomatischen Behandlung schmerzhafter Verspannungen der Skelettmuskulatur.
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Orphenadrine (sold under many brand names) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine. It is a muscle relaxant that is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs. This substance is considered a dirty drug due to its multiple mechanism of action in different pathways. It was discovered and developed in the 1940s.
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L'orfenadrina è un antagonista dei recettori colinergici dotato di preminente attività sul sistema nervoso centrale, ma anche di azioni periferiche. Viene utilizzato per il trattamento degli spasmi muscolari dolorosi e condizioni simili, nonché per il trattamento di alcuni sintomi della malattia di Parkinson. In Italia il farmaco è venduto dalla società farmaceutica Astellas Pharma S.p.A. con il nome commerciale di Disipal nella forma farmaceutica di compresse rivestite contenenti 50 mg di principio attivo.
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A orfenadrina (citrato/cloridrato) é um fármaco anticolinérgico relaxante muscular, com baixa atividade anti-histamínica. Antagonista dos receptores colinérgicos muscarínicos centrais e periféricos que produz diminuição do tônus muscular, sem alterações centrais de importância. É também utilizada no tratamento da Doença de Parkinson. É utilizada para reduzir a dor ligada a traumatismos (contraturas) musculares ou inflatórios musculares, geralmente associada a um analgésico (ex:.Dorflex® - dipirona sódica + cafeína anidra + citrato de orfenadrina). Foi sintetizada pela primeira vez no final de 1940.
rdf:langString
Η ορφεναδρίνη (αγγλ. orphenadrine) είναι χημική δραστική ένωση, που πωλείται με πολλές φαρμακευτικές επωνυμίες παγκοσμίως, και αποτελεί ένα αντιχολινεργικό φάρμακο της κατηγορίας των αντιισταμινικών με βάση την αιθανολαμίνη. Χημικώς, σχετίζεται στενά με τη διφαινυδραμίνη.
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أورفينادرين
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Orphenadrin
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Ορφεναδρίνη
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Orfenadrina
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Orphenadrine
rdf:langString
Orfenadrina
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1983341
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BC01
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Renal and biliary
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-N,N-Dimethyl-2-[-phenyl-methoxy]-ethanamine
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D08305
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POM
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Rx-only
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a682162
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C
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Oral, intravenous, intramuscular
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OCc2ccccc2C
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QVYRGXJJSLMXQH-UHFFFAOYSA-N
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background:#ccccff
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Generic; many brand names
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AL805O9OG9
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(Orphenadrine) مناهض مسكاريني
rdf:langString
Orphenadrin ist ein zentral wirksamer Arzneistoff, der die Skelettmuskulatur entspannt und damit zu den Muskelrelaxanzien zählt. Orphenadrin gehört zur Klasse der H1-Antihistaminika und ist chemisch verwandt mit Diphenhydramin. Es wird angewendet zur symptomatischen Behandlung schmerzhafter Verspannungen der Skelettmuskulatur.
rdf:langString
Η ορφεναδρίνη (αγγλ. orphenadrine) είναι χημική δραστική ένωση, που πωλείται με πολλές φαρμακευτικές επωνυμίες παγκοσμίως, και αποτελεί ένα αντιχολινεργικό φάρμακο της κατηγορίας των αντιισταμινικών με βάση την αιθανολαμίνη. Χημικώς, σχετίζεται στενά με τη διφαινυδραμίνη. Χρησιμοποιείται για τη θεραπεία του μυϊκού πόνου, και επίσης για να βοηθήσει στη νόσο του Πάρκινσον, σήμερα ωστόσο, έχει αντικατασταθεί σε μεγάλο βαθμό από νέας γενιάς φάρμακα. Αυτή η χημική δραστική ουσία θεωρείται ως dirty drug (βρώμικο φάρμακο) λόγω του πολλαπλού μηχανισμού δράσης της σε διαφορετικές βιοχημικές οδούς. Ανακαλύφθηκε και αναπτύχθηκε τη δεκαετία του 1940.
rdf:langString
Orphenadrine (sold under many brand names) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine. It is a muscle relaxant that is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs. This substance is considered a dirty drug due to its multiple mechanism of action in different pathways. It was discovered and developed in the 1940s.
rdf:langString
L'orfenadrina è un antagonista dei recettori colinergici dotato di preminente attività sul sistema nervoso centrale, ma anche di azioni periferiche. Viene utilizzato per il trattamento degli spasmi muscolari dolorosi e condizioni simili, nonché per il trattamento di alcuni sintomi della malattia di Parkinson. In Italia il farmaco è venduto dalla società farmaceutica Astellas Pharma S.p.A. con il nome commerciale di Disipal nella forma farmaceutica di compresse rivestite contenenti 50 mg di principio attivo.
rdf:langString
A orfenadrina (citrato/cloridrato) é um fármaco anticolinérgico relaxante muscular, com baixa atividade anti-histamínica. Antagonista dos receptores colinérgicos muscarínicos centrais e periféricos que produz diminuição do tônus muscular, sem alterações centrais de importância. É também utilizada no tratamento da Doença de Parkinson. É utilizada para reduzir a dor ligada a traumatismos (contraturas) musculares ou inflatórios musculares, geralmente associada a um analgésico (ex:.Dorflex® - dipirona sódica + cafeína anidra + citrato de orfenadrina). Foi sintetizada pela primeira vez no final de 1940.
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7251
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S4
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OTC
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B2
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95.0
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90.0
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16945
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Generic; many brand names
xsd:string
83-98-7
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7789
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900
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DB01173
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AL805O9OG9
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D08305
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a682162
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4601
