Bentley compounds
http://dbpedia.org/resource/Bentley_compounds
The Bentley compounds are a class of semi-synthetic opioids that were first synthesized by by Diels-Alder reaction of thebaine with various dienophiles. The compounds are also known as thevinols, orvinols, or bridged oripavine derivatives, due to the characteristic 6,14-endo-ethano- or etheno-bridge and substitution at the 7α position. Buprenorphine and etorphine are perhaps the best known of the family, which was the first series of extremely potent μ-opioid agonists, with some compounds in the series having over many thousands of times the analgesic potency of morphine.
rdf:langString
rdf:langString
Bentley compounds
xsd:integer
31911962
xsd:integer
1095706104
rdf:langString
The Bentley compounds are a class of semi-synthetic opioids that were first synthesized by by Diels-Alder reaction of thebaine with various dienophiles. The compounds are also known as thevinols, orvinols, or bridged oripavine derivatives, due to the characteristic 6,14-endo-ethano- or etheno-bridge and substitution at the 7α position. Buprenorphine and etorphine are perhaps the best known of the family, which was the first series of extremely potent μ-opioid agonists, with some compounds in the series having over many thousands of times the analgesic potency of morphine.
xsd:nonNegativeInteger
3205