Upstream and downstream (transduction)
http://dbpedia.org/resource/Upstream_and_downstream_(transduction)
The upstream signaling pathway is triggered by the binding of a signaling molecule, a ligand, to a receiving molecule, a receptor. Receptors and ligands exist in many different forms, and only recognize/bond to particular molecules. Upstream extracellular signaling transduce a variety of intracellular cascades. Receptors and ligands are common upstream signaling molecules that dictate the downstream elements of the signal pathway. A plethora of different factors affect which ligands bind to which receptors and the downstream cellular response that they initiate.
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Em biologia molecular, os termos a montante e a jusante podem se referir à ordem temporal e mecanicista de eventos celulares e moleculares. Por exemplo, na transdução de sinal, o segundo mensageiro atua a jusante da ativação de receptores de membrana celular. O outro caminho, a ativação de receptores da membrana celular ocorre a montante da produção de segundos mensageiros.
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A montante e a jusante (transdução)
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Upstream and downstream (transduction)
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1105390472
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The upstream signaling pathway is triggered by the binding of a signaling molecule, a ligand, to a receiving molecule, a receptor. Receptors and ligands exist in many different forms, and only recognize/bond to particular molecules. Upstream extracellular signaling transduce a variety of intracellular cascades. Receptors and ligands are common upstream signaling molecules that dictate the downstream elements of the signal pathway. A plethora of different factors affect which ligands bind to which receptors and the downstream cellular response that they initiate.
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Em biologia molecular, os termos a montante e a jusante podem se referir à ordem temporal e mecanicista de eventos celulares e moleculares. Por exemplo, na transdução de sinal, o segundo mensageiro atua a jusante da ativação de receptores de membrana celular. O outro caminho, a ativação de receptores da membrana celular ocorre a montante da produção de segundos mensageiros.
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7363
