U-50488

http://dbpedia.org/resource/U-50488 an entity of type: Thing

U-50488 is a drug which acts as a highly selective κ-opioid agonist, but without any μ-opioid antagonist effects. It has analgesic, diuretic and antitussive effects, and reverses the memory impairment produced by anticholinergic drugs. U-50488 was one of the first selective kappa agonists invented and research on its derivatives has led to the development of a large family of related compounds. This compound has never received FDA approval and there are no reported human cases in the literature involving an U-50488 overdose. rdf:langString
rdf:langString U-50488
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xsd:integer 1081898413
rdf:langString Ball-and-stick model of the U-50488 molecule
xsd:integer 19
xsd:integer 67198
xsd:integer 73358
xsd:integer 441765
xsd:integer 2300345
xsd:integer 2
xsd:integer 26
rdf:langString U-50488 molecule ball.png
xsd:integer 2
xsd:integer 2
xsd:integer 1
xsd:integer 3036289
rdf:langString CNCCC3=CCCl
xsd:integer 1
rdf:langString VQLPLYSROCPWFF-QZTJIDSGSA-N
xsd:integer 39
rdf:langString changed
xsd:integer 405766426
rdf:langString changed
xsd:integer 200
rdf:langString U-50488 is a drug which acts as a highly selective κ-opioid agonist, but without any μ-opioid antagonist effects. It has analgesic, diuretic and antitussive effects, and reverses the memory impairment produced by anticholinergic drugs. U-50488 was one of the first selective kappa agonists invented and research on its derivatives has led to the development of a large family of related compounds. This compound has never received FDA approval and there are no reported human cases in the literature involving an U-50488 overdose.
xsd:integer 1652
xsd:nonNegativeInteger 4867
xsd:string 67198-13-4
xsd:string 73358
xsd:string 441765
xsd:string 39K8JHE8XN
xsd:string 3036289

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