Trospium chloride
http://dbpedia.org/resource/Trospium_chloride an entity of type: Thing
Trospium ist ein Arzneistoff aus der Gruppe der Tropanderivate und gehört zu den synthetischen Anticholinergika. Chemisch handelt es sich um ein quartäres 3α-, das mit Benzilsäure verestert ist. Er wird zur Behandlung der Drang- und Reflexinkontinenz eingesetzt.
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Tróspio ou cloreto de tróspio é um fármaco utilizado pela medicina como antiespasmódico de vias urinárias, nas situações de bexiga hiperativa, incontinência urinária, nictúria, polaciúria e distúrbios urodinâmicos. É um fármaco sintético, que apresenta potentes efeitos antimuscarínicos (nos receptores M1 e M3 principalmente) e ganglioplégicos. Este medicamento apresenta baixa toxicidade e é eliminado inalterado na urina.
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Trospium chloride is used to treat overactive bladder. It has side effects typical of drugs like it, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed. However it doesn't cause central nervous system side effects like other drugs of its class. It is pregnancy category C and is excreted somewhat in breast milk. Chemically it is a quaternary ammonium cation which causes it to stay in periphery rather than crossing the blood–brain barrier. It works by causing the smooth muscle in the bladder to relax.
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Trospiumchlorid
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Tróspio
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Trospium chloride
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6419517
xsd:integer
1086676885
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BD09
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G04
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25
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10405
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32270
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1201344
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10482307
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1
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DB00209
<second>
72000.0
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30
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3
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Rx-only
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1
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3
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C
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107979
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By mouth
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OCCO[C@@H]3C[C@@H]5CC[C@H][N+]45CCCC4
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1
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OYYDSUSKLWTMMQ-JKHIJQBDSA-N
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Regurin, Sanctura, many generics
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402706794
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Trospium ist ein Arzneistoff aus der Gruppe der Tropanderivate und gehört zu den synthetischen Anticholinergika. Chemisch handelt es sich um ein quartäres 3α-, das mit Benzilsäure verestert ist. Er wird zur Behandlung der Drang- und Reflexinkontinenz eingesetzt.
rdf:langString
Trospium chloride is used to treat overactive bladder. It has side effects typical of drugs like it, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed. However it doesn't cause central nervous system side effects like other drugs of its class. It is pregnancy category C and is excreted somewhat in breast milk. Chemically it is a quaternary ammonium cation which causes it to stay in periphery rather than crossing the blood–brain barrier. It works by causing the smooth muscle in the bladder to relax. It was patented in 1966 and approved for medical use in 1974. It was first approved in the US in 2004, and an extended release version with once-daily dosing was brought to market in 2007. It became generic in Europe in 2009 and in the US the first extended-release generic was approved in 2012.
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Tróspio ou cloreto de tróspio é um fármaco utilizado pela medicina como antiespasmódico de vias urinárias, nas situações de bexiga hiperativa, incontinência urinária, nictúria, polaciúria e distúrbios urodinâmicos. É um fármaco sintético, que apresenta potentes efeitos antimuscarínicos (nos receptores M1 e M3 principalmente) e ganglioplégicos. Este medicamento apresenta baixa toxicidade e é eliminado inalterado na urina.
xsd:integer
50
xsd:nonNegativeInteger
17674
rdf:langString
Regurin, Sanctura, many generics
xsd:string
10405-02-4
xsd:string
32270
xsd:string
1201344
xsd:string
DB00209
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1E6682427E
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107979