Triphenylmethylethylene

http://dbpedia.org/resource/Triphenylmethylethylene an entity of type: Thing

Triphenylmethylethylene, also known as methyltriphenylethylene or as triphenylpropene, is a synthetic nonsteroidal estrogen of the triphenylethylene group that is related to triphenylchloroethylene and was never marketed. Along with diethylstilbestrol and triphenylchoroethylene, triphenylmethylethylene was studied in 1944 by Sir Alexander Haddow for the treatment of breast cancer, and this is historically notable in that it was the first time that high-dose estrogens were found to be effective in the treatment of breast cancer. However, while diethylstilbestrol and triphenylchloroethylene were found to be significantly effective, triphenylmethylethylene was less effective and showed a favorable response in only 1 of 4 treated cases. rdf:langString
rdf:langString Triphenylmethylethylene
xsd:integer 52626525
xsd:integer 1015321525
xsd:integer 21
xsd:integer 3677
xsd:integer 3417659
xsd:integer 18
xsd:integer 11
xsd:integer 4207747
rdf:langString CCC3=CC=CC=C3
xsd:integer 1
rdf:langString FLTIZNYOOOPPHQ-UHFFFAOYSA-N
rdf:langString Methyltriphenylethylene; Triphenylpropene
xsd:integer 200
rdf:langString Triphenylmethylethylene, also known as methyltriphenylethylene or as triphenylpropene, is a synthetic nonsteroidal estrogen of the triphenylethylene group that is related to triphenylchloroethylene and was never marketed. Along with diethylstilbestrol and triphenylchoroethylene, triphenylmethylethylene was studied in 1944 by Sir Alexander Haddow for the treatment of breast cancer, and this is historically notable in that it was the first time that high-dose estrogens were found to be effective in the treatment of breast cancer. However, while diethylstilbestrol and triphenylchloroethylene were found to be significantly effective, triphenylmethylethylene was less effective and showed a favorable response in only 1 of 4 treated cases.
xsd:nonNegativeInteger 4062
xsd:string 3677-70-1
xsd:string 4207747

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