Toxic anterior segment syndrome
http://dbpedia.org/resource/Toxic_anterior_segment_syndrome an entity of type: Thing
A Síndrome tóxica do segmento anterior ou TASS (do inglês, Toxic Anterior Segment Syndrome) é uma complicação rara, porém muito exuberante e que ocorre após uma cirurgia intraocular. TASS é uma forte reação estéril inflamatória da câmara anterior do olho, acompanhada de edema corneano difuso, que acontece entre 12 e 48 horas depois de uma cirurgia de segmento anterior, tipicamente para correção de catarata. A sintomatologia é compatível com a de uma endoftalmite não infecciosa, com ou sem dor, diminuição marcada da visão, edema corneano difuso, fotofobia e forte reação de câmara anterior, ocasionalmente com hipopion. Na maior parte dos casos, a condição responde bem ao tratamento com corticoides tópicos.
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Toxic anterior segment syndrome is an acute, sterile anterior segment inflammation following generally uneventful cataract and anterior segment surgery. One of the main factors in differentiating toxic anterior segment syndrome from an infectious endophthalmitis is the rapid onset. Most patients with toxic anterior segment syndrome will develop symptoms within 12 to 24 hours of the surgery. Common findings on anterior segment slit lamp examination include increased cell and flare with associated fibrin and possible hypopyon formation. Patients may show signs of diffuse corneal edema, and they may also show signs of iris atrophy with pupillary abnormalities and eventual increased intraocular pressure.
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Síndrome tóxica do segmento anterior
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Toxic anterior segment syndrome
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ophthalmology
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Toxic anterior segment syndrome is an acute, sterile anterior segment inflammation following generally uneventful cataract and anterior segment surgery. One of the main factors in differentiating toxic anterior segment syndrome from an infectious endophthalmitis is the rapid onset. Most patients with toxic anterior segment syndrome will develop symptoms within 12 to 24 hours of the surgery. Common findings on anterior segment slit lamp examination include increased cell and flare with associated fibrin and possible hypopyon formation. Patients may show signs of diffuse corneal edema, and they may also show signs of iris atrophy with pupillary abnormalities and eventual increased intraocular pressure. It is important to differentiate sterile postoperative inflammation from infectious endophthalmitis because the treatments of these patients are markedly different. Patients with toxic anterior segment syndrome will often respond rapidly to treatment with topical corticosteroids, while infectious endophthalmitis must be treated with antibiotics. It is important that the patients be evaluated often to ensure that the inflammation is clearing and that the patient's intraocular pressure is under control. The clearing of the inflammation and eventual patient outcome is related to the severity of the toxic insult at the time of surgery. Most patients reported to date are in the category of a moderate toxic inflammation. Toxic anterior segment syndrome may be related to problems with any irrigating solution or other solution placed in the patient's eye during surgery, including balanced salt solution or anything added to solutions. Material placed in the eye during surgery such as anesthetics, ophthalmic viscoelastic devices, antibiotics, or other medications has been associated with toxic anterior segment syndrome. Problems related to the cleaning and sterilization of instruments for cataract surgery have been found to be a cause.
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A Síndrome tóxica do segmento anterior ou TASS (do inglês, Toxic Anterior Segment Syndrome) é uma complicação rara, porém muito exuberante e que ocorre após uma cirurgia intraocular. TASS é uma forte reação estéril inflamatória da câmara anterior do olho, acompanhada de edema corneano difuso, que acontece entre 12 e 48 horas depois de uma cirurgia de segmento anterior, tipicamente para correção de catarata. A sintomatologia é compatível com a de uma endoftalmite não infecciosa, com ou sem dor, diminuição marcada da visão, edema corneano difuso, fotofobia e forte reação de câmara anterior, ocasionalmente com hipopion. Na maior parte dos casos, a condição responde bem ao tratamento com corticoides tópicos.
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