Tegaserod

http://dbpedia.org/resource/Tegaserod an entity of type: Thing

Tegaserod ist ein Arzneistoff zur Behandlung des Reizdarmsyndroms (IBS) mit Verstopfung (Obstipation) bei Frauen. Unter den Handelsnamen Zelnorm (Novartis) wurde es 2002 in den USA zugelassen. Die Wirkung entsteht durch Aktivierung der 5-HT-Rezeptoren (Serotoninagonist). rdf:langString

تيجاسيرود أو تيغاسيرود (بالإنجليزية: Tegaserod)‏ هو ناهض 5-HT4 مصنع من قبل شركة Novartis ويباع تحت اسم Zelnorm وZelmac ويستخدم لعلاج متلازمة القولون العصبي والإمساك. rdf:langString

El Tegaserod es un fármaco agonista parcial de los receptores de serotonina 5-HT4, desarrollado por Novartis. rdf:langString

Tegaserod is a 5-HT4 agonist manufactured by Novartis and sold under the names Zelnorm and Zelmac for the management of irritable bowel syndrome and constipation. Approved by the FDA in 2002, it was subsequently removed from the market in 2007 due to FDA concerns about possible adverse cardiovascular effects. Before then, it was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating, and constipation associated with irritable bowel syndrome. Its use was also approved to treat chronic idiopathic constipation. rdf:langString

Tegaserode é um fármaco agonista parcial dos receptores 5-HT4 da serotonina. Tem como principais funções agir contra os efeitos da constipação intestinal crônica e síndrome do cólon irritável. rdf:langString

Тегасерод — синтетичний лікарський засіб, що застосовується для лікування захворювань травної системи, який є стимулятором серотонінових рецепторів, та має прокінетичну дію, що застосовується перорально. rdf:langString

Tegaserod è un agonista dei recettori 5-HT4, utilizzato per il trattamento della sindrome dell'intestino irritabile e della costipazione. Il farmaco è prodotto e venduto dalla società farmaceutica Novartis con il nome commerciale di Zelnorm e Zelmac. Approvato dalla Food and Drug Administration (FDA) degli USA nel 2002, è stato successivamente ritirato dal mercato nel 2007, a causa delle preoccuppazioni della FDA circa i possibili effetti avversi cardiovascolari. Prima di allora tegaserod era l'unico farmaco approvato dalla FDA per contribuire ad alleviare il disagio addominale, il senso di gonfiore e la costipazione associata alla sindrome del colon irritabile. Il suo uso era stato approvato anche per il trattamento della costipazione idiopatica cronica. Attualmente, tegaserod può essere rdf:langString

rdfs:label

rdf:langString تيجاسيرود

rdf:langString Tegaserod

rdf:langString Tegaserode

rdf:langString Tegaserod

rdf:langString Тегасерод

dbpedia-owl:wikiPageID

xsd:integer 1167677

dbpedia-owl:wikiPageRevisionID

xsd:integer 1083517293

dbpprop:atcSuffix

rdf:langString AX06

dbpprop:atcPrefix

rdf:langString A06

dbpprop:bioavailability

<perCent> 10.0

dbpprop:c

xsd:integer 16

dbpprop:casNumber

xsd:integer 145158

dbpprop:chembl

xsd:integer 76370

dbpprop:chemspiderid

xsd:integer 10609889

dbpprop:drugbank

rdf:langString DB01079

dbpprop:eliminationHalfLife

<second> 18000.0

dbpprop:excretion

rdf:langString Fecal and renal

dbpprop:h

xsd:integer 23

dbpprop:image

rdf:langString Tegaserod ball-and-stick model.png

dbpprop:iupacName

xsd:integer -2

dbpprop:kegg

rdf:langString D02730

dbpprop:legalUsComment

rdf:langString Usage requires authorization from the FDA

dbpprop:metabolism

rdf:langString Gastric and hepatic

dbpprop:n

xsd:integer 5

dbpprop:o

xsd:integer 1

dbpprop:pregnancyUs

rdf:langString B

dbpprop:pubchem

xsd:integer 5362436

dbpprop:routesOfAdministration

rdf:langString Oral

dbpprop:smiles

rdf:langString CCCCCNCNN=Cc1c[nH]c2ccccc12

dbpprop:stdinchi

xsd:integer 1

dbpprop:stdinchikey

rdf:langString IKBKZGMPCYNSLU-RGVLZGJSSA-N

dbpprop:tradename

rdf:langString Zelnorm, Zelmac

dbpprop:unii

xsd:integer 458

dbpprop:verifiedfields

rdf:langString changed

dbpprop:verifiedrevid

xsd:integer 470478621

dbpprop:watchedfields

rdf:langString changed

dbpprop:width

xsd:integer 250

dbpedia-owl:abstract

rdf:langString Tegaserod ist ein Arzneistoff zur Behandlung des Reizdarmsyndroms (IBS) mit Verstopfung (Obstipation) bei Frauen. Unter den Handelsnamen Zelnorm (Novartis) wurde es 2002 in den USA zugelassen. Die Wirkung entsteht durch Aktivierung der 5-HT-Rezeptoren (Serotoninagonist).

rdf:langString تيجاسيرود أو تيغاسيرود (بالإنجليزية: Tegaserod)‏ هو ناهض 5-HT4 مصنع من قبل شركة Novartis ويباع تحت اسم Zelnorm وZelmac ويستخدم لعلاج متلازمة القولون العصبي والإمساك.

rdf:langString El Tegaserod es un fármaco agonista parcial de los receptores de serotonina 5-HT4, desarrollado por Novartis.

rdf:langString Tegaserod is a 5-HT4 agonist manufactured by Novartis and sold under the names Zelnorm and Zelmac for the management of irritable bowel syndrome and constipation. Approved by the FDA in 2002, it was subsequently removed from the market in 2007 due to FDA concerns about possible adverse cardiovascular effects. Before then, it was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating, and constipation associated with irritable bowel syndrome. Its use was also approved to treat chronic idiopathic constipation.

rdf:langString Tegaserod è un agonista dei recettori 5-HT4, utilizzato per il trattamento della sindrome dell'intestino irritabile e della costipazione. Il farmaco è prodotto e venduto dalla società farmaceutica Novartis con il nome commerciale di Zelnorm e Zelmac. Approvato dalla Food and Drug Administration (FDA) degli USA nel 2002, è stato successivamente ritirato dal mercato nel 2007, a causa delle preoccuppazioni della FDA circa i possibili effetti avversi cardiovascolari. Prima di allora tegaserod era l'unico farmaco approvato dalla FDA per contribuire ad alleviare il disagio addominale, il senso di gonfiore e la costipazione associata alla sindrome del colon irritabile. Il suo uso era stato approvato anche per il trattamento della costipazione idiopatica cronica. Attualmente, tegaserod può essere utilizzato solo in situazioni di emergenza e solo previa autorizzazione da parte della FDA.

rdf:langString Tegaserode é um fármaco agonista parcial dos receptores 5-HT4 da serotonina. Tem como principais funções agir contra os efeitos da constipação intestinal crônica e síndrome do cólon irritável.

rdf:langString Тегасерод — синтетичний лікарський засіб, що застосовується для лікування захворювань травної системи, який є стимулятором серотонінових рецепторів, та має прокінетичну дію, що застосовується перорально.

dbpprop:iupharLigand

xsd:integer 226

dbpprop:pregnancyAu

rdf:langString B3

dbpprop:proteinBound

<perCent> 98.0

dbpedia-owl:bioavailability

xsd:float 10.0

dbpedia-owl:wikiPageLength

xsd:nonNegativeInteger 7194

dbpedia-owl:alternativeName

rdf:langString Zelnorm, Zelmac