Tamibarotene
http://dbpedia.org/resource/Tamibarotene an entity of type: Thing
Tamibarotene (brand name: Amnolake), also called retinobenzoic acid, is orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity against acute promyelocytic leukaemia (APL) . It is currently marketed only in Japan and early trials have demonstrated that it tends to be better tolerated than ATRA. It has also been investigated as a possible treatment for Alzheimer's disease, multiple myeloma and Crohn's disease. Tamibarotene is found to have inhibitory potential for the viral spike protein of Omicron variant of SARS-CoV2 and can be a potential candidate for developing potential therapeutics for the treatment of omicron variant of COVID19.
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タミバロテン（Tamibarotene）は別名、レチノ安息香酸とも呼ばれる合成レチノイドであり、トレチノイン（ATRA）耐性急性前骨髄球性白血病（APL）に対する化学療法剤として用いられる経口剤である。商品名アムノレイク。日本でのみ承認（2005年4月）されており、早期臨床試験でATRAより良好な忍容性が示されている。他に、アルツハイマー型認知症、多発性骨髄腫、クローン病治療への応用が模索されている。開発コードAm80、TOS-80T。
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Tamibarotene é um fármaco experimental com propriedade contra o câncer. Existe relato de cura de um paciente com uma forma rara de leucemia, realizado por cientistas da University of Texas Southwestern Medical Center. Quimicamente trata-se de um retinoide.
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タミバロテン
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Tamibarotene
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Tamibarotene
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25398779
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Tamibarotene2DACS.svg
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4
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Tamibarotene (brand name: Amnolake), also called retinobenzoic acid, is orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity against acute promyelocytic leukaemia (APL) . It is currently marketed only in Japan and early trials have demonstrated that it tends to be better tolerated than ATRA. It has also been investigated as a possible treatment for Alzheimer's disease, multiple myeloma and Crohn's disease. Tamibarotene is found to have inhibitory potential for the viral spike protein of Omicron variant of SARS-CoV2 and can be a potential candidate for developing potential therapeutics for the treatment of omicron variant of COVID19.
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タミバロテン（Tamibarotene）は別名、レチノ安息香酸とも呼ばれる合成レチノイドであり、トレチノイン（ATRA）耐性急性前骨髄球性白血病（APL）に対する化学療法剤として用いられる経口剤である。商品名アムノレイク。日本でのみ承認（2005年4月）されており、早期臨床試験でATRAより良好な忍容性が示されている。他に、アルツハイマー型認知症、多発性骨髄腫、クローン病治療への応用が模索されている。開発コードAm80、TOS-80T。
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Tamibarotene é um fármaco experimental com propriedade contra o câncer. Existe relato de cura de um paciente com uma forma rara de leucemia, realizado por cientistas da University of Texas Southwestern Medical Center. Quimicamente trata-se de um retinoide.
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3316
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4-[(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid
