THIQ
http://dbpedia.org/resource/THIQ an entity of type: Thing
THIQ is a drug used in scientific research, which is the first non-peptide agonist developed that is selective for the melanocortin receptor subtype MC4. In animal studies, THIQ stimulated sexual activity in rats, but with little effect on appetite or inflammation. This supports possible application of MC4 selective agonists for the treatment of sexual dysfunction in humans, although THIQ itself has poor oral bioavailability and a short duration of action so improved analogues will need to be developed.
rdf:langString
rdf:langString
THIQ
xsd:integer
23438192
xsd:integer
1073189955
xsd:integer
33
xsd:integer
312637
xsd:integer
8114027
xsd:integer
1
xsd:integer
41
rdf:langString
N-[-1,2,3,4-tetrahydroisoquinolinium-3-ylcarbonyl]--1- -2-[4-cyclohexyl-4-piperidin-1-yl]-2-oxoethylamine
xsd:double
589.169
xsd:integer
6
xsd:integer
2
xsd:integer
9938402
rdf:langString
C1CCCC2CN6C=NC=N6
xsd:integer
1
rdf:langString
HLCHESOMJVGDSJ-LOYHVIPDSA-N
xsd:integer
451219622
rdf:langString
THIQ is a drug used in scientific research, which is the first non-peptide agonist developed that is selective for the melanocortin receptor subtype MC4. In animal studies, THIQ stimulated sexual activity in rats, but with little effect on appetite or inflammation. This supports possible application of MC4 selective agonists for the treatment of sexual dysfunction in humans, although THIQ itself has poor oral bioavailability and a short duration of action so improved analogues will need to be developed.
xsd:integer
1338
xsd:nonNegativeInteger
4986
xsd:string
312637-48-2
xsd:string
9938402