Sulfonylurea receptor
http://dbpedia.org/resource/Sulfonylurea_receptor an entity of type: Thing
Рецепторы сульфонилмочевины (англ. sulfonylurea receptors; более известны в виде акронима SUR) — мембранные белки, которые являются мишенями сульфонилмочевины и её производных. Представляют собой субъединицы АТФ-чувствительных калиевых ионных каналов.
rdf:langString
In molecular biology, the sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of antidiabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2). The association of four Kir6.x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel.
rdf:langString
rdf:langString
Sulfonylurea receptor
rdf:langString
Рецептор сульфонилмочевины
rdf:langString
ATP-binding cassette, subfamily C (CFTR/MRP), member 9
rdf:langString
ATP-binding cassette, subfamily C (CFTR/MRP), member 8
rdf:langString
ATP-binding cassette, subfamily C , member 8
rdf:langString
ATP-binding cassette, subfamily C , member 9
xsd:integer
10224700
xsd:integer
1115979497
xsd:integer
600509
601439
rdf:langString
SUR1
rdf:langString
SUR2A, SUR2B
rdf:langString
O60706
rdf:langString
Q09428
rdf:langString
In molecular biology, the sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of antidiabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2). The association of four Kir6.x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. Three forms of the sulfonylurea receptor are known, SUR1 encoded by the ABCC8 gene, and SUR2A and SUR2B, which are splice variants arising from a single ABCC9 gene.
rdf:langString
Рецепторы сульфонилмочевины (англ. sulfonylurea receptors; более известны в виде акронима SUR) — мембранные белки, которые являются мишенями сульфонилмочевины и её производных. Представляют собой субъединицы АТФ-чувствительных калиевых ионных каналов.
rdf:langString
p
xsd:double
12.1
15.1
xsd:integer
11
12
xsd:integer
6833
10060
xsd:integer
59
60
rdf:langString
NM_000352
rdf:langString
NM_005691
xsd:string
p
xsd:string
12.1
15.1
xsd:string
11
12
xsd:string
10060
6833
xsd:string
60
59
xsd:string
NM_000352
xsd:string
NM_005691
xsd:string
O60706
Q09428
xsd:nonNegativeInteger
6694
xsd:integer
600509
601439
xsd:string
ABCC8
xsd:string
ABCC9
xsd:string
SUR1
xsd:string
SUR2A, SUR2B