Sphingosine kinase

http://dbpedia.org/resource/Sphingosine_kinase an entity of type: Thing

Une sphingosine kinase (SphK) est une enzyme (en l'occurrence une kinase) qui catalyse la conversion de la sphingosine en sphingosine-1-phosphate (S1P : un sphingolipide de signalisation cellulaire, qui agit comme un médiateur lipidique bioactif) par phosphorylation (addition d'un groupe phosphoryle —PO32−). Dans la nomenclature EC, les sphingosine kinases portent la référence EC 2.7.1.91. rdf:langString
Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine. Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate, are lipid second messengers involved in diverse cellular processes. There are two forms of SphK, SphK1 and SphK2. SphK1 is found in the cytosol of eukaryotic cells, and migrates to the plasma membrane upon activation. SphK2 is localized to the nucleus. rdf:langString
rdf:langString Sphingosine kinase
rdf:langString Sphingosine kinase
rdf:langString sphinganine kinase
rdf:langString sphinganine kinase
xsd:integer 4568160
xsd:integer 1109705795
xsd:integer 603730 607092
rdf:langString Sphingosine kinase 1, hexamer, Human
xsd:integer 50864
xsd:double 2.7
xsd:double 2.7
xsd:integer 8481
xsd:integer 2
rdf:langString Q9NRA0
rdf:langString Q9NYA1
xsd:integer 270
rdf:langString Une sphingosine kinase (SphK) est une enzyme (en l'occurrence une kinase) qui catalyse la conversion de la sphingosine en sphingosine-1-phosphate (S1P : un sphingolipide de signalisation cellulaire, qui agit comme un médiateur lipidique bioactif) par phosphorylation (addition d'un groupe phosphoryle —PO32−). Dans la nomenclature EC, les sphingosine kinases portent la référence EC 2.7.1.91.
rdf:langString Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine. Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate, are lipid second messengers involved in diverse cellular processes. There are two forms of SphK, SphK1 and SphK2. SphK1 is found in the cytosol of eukaryotic cells, and migrates to the plasma membrane upon activation. SphK2 is localized to the nucleus.
rdf:langString q
xsd:double 13.2 25.2
xsd:integer 17 19
xsd:integer 8877 56848
xsd:integer 11240 18859
rdf:langString NM_020126
rdf:langString NM_182965
xsd:nonNegativeInteger 6032
xsd:string 2.7.1.91

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