Ruthenium red
http://dbpedia.org/resource/Ruthenium_red an entity of type: Thing
Rutheniumrot, auch als Ruthenrot bezeichnet, ist ein Komplexsalz des Metalles Ruthenium, das als Farbstoff in der botanischen und zoologischen Histologie zur Anfärbung spezifischer Polysaccharidstrukturen verwendet wird. Nach der chemischen Nomenklatur lautet der Name: Tetradecaammin-di-µ-oxo-triruthenium(III,IV)-hexachlorid-Hydrat mit der Halbstrukturformel [(NH3)5Ru3+-O-Ru4+(NH3)4-O-Ru3+(NH3)5]Cl6·H2O.
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Rosso di rutenio è un colorante usato in biologia per evidenziare la presenza di emicellulose e pectine colorando la parete cellulare vegetale in rosa. I tessuti più adatti per questa reazione colorimetrica sono i collenchimi, nei quali i marcati aspessimenti parietali sono la conseguenza dell'apposizione di sostanze pectiche ed emicellulosa. Gli apparati più adatti per questo tipo di colorazione sono quelli che presentano un'abbondanza di tessuto collenchimatico.
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The inorganic dye ammoniated ruthenium oxychloride, also known as ruthenium red, is used in histology to stain aldehyde fixed mucopolysaccharides. Ruthenium red (RR) has also been used as a pharmacological tool to study specific cellular mechanisms. Selectivity is a significant issue in such studies as RR is known to interact with many proteins. These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, , , CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase, mitochondrial Ca2+ uniporter, tubulin, myosin light-chain phosphatase, and Ca2+ binding proteins such as calmodulin. Ruthenium red displays nanomolar potency against several of its binding partners (e.g. TRPV4, ryanodine receptors,...). For example, it is a potent
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Rutheniumrot
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Rosso di rutenio
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Ruthenium red
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Ammoniated ruthenium oxychloride
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Ammoniated ruthenium oxychloride
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Ruthenium red cation.svg
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changed
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Rutheniumrot, auch als Ruthenrot bezeichnet, ist ein Komplexsalz des Metalles Ruthenium, das als Farbstoff in der botanischen und zoologischen Histologie zur Anfärbung spezifischer Polysaccharidstrukturen verwendet wird. Nach der chemischen Nomenklatur lautet der Name: Tetradecaammin-di-µ-oxo-triruthenium(III,IV)-hexachlorid-Hydrat mit der Halbstrukturformel [(NH3)5Ru3+-O-Ru4+(NH3)4-O-Ru3+(NH3)5]Cl6·H2O.
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The inorganic dye ammoniated ruthenium oxychloride, also known as ruthenium red, is used in histology to stain aldehyde fixed mucopolysaccharides. Ruthenium red (RR) has also been used as a pharmacological tool to study specific cellular mechanisms. Selectivity is a significant issue in such studies as RR is known to interact with many proteins. These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, , , CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase, mitochondrial Ca2+ uniporter, tubulin, myosin light-chain phosphatase, and Ca2+ binding proteins such as calmodulin. Ruthenium red displays nanomolar potency against several of its binding partners (e.g. TRPV4, ryanodine receptors,...). For example, it is a potent inhibitor of intracellular calcium release by ryanodine receptors (Kd ~20 nM). As a TRPA1 blocker, it assists in reducing the airway inflammation caused by pepper spray. RR has been used on plant material since 1890 for staining pectins, mucilages, and gums. RR is a stereoselective stain for pectic acid, insofar as the staining site occurs between each monomer unit and the next adjacent neighbor.
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Rosso di rutenio è un colorante usato in biologia per evidenziare la presenza di emicellulose e pectine colorando la parete cellulare vegetale in rosa. I tessuti più adatti per questa reazione colorimetrica sono i collenchimi, nei quali i marcati aspessimenti parietali sono la conseguenza dell'apposizione di sostanze pectiche ed emicellulosa. Gli apparati più adatti per questo tipo di colorazione sono quelli che presentano un'abbondanza di tessuto collenchimatico.
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6046