Rolapitant
http://dbpedia.org/resource/Rolapitant an entity of type: Thing
Rolapitant (INN, trade name Varubi /vəˈruːbi/ və-ROO-bee in the US and Varuby in the European Union) is a drug originally developed by Schering-Plough and licensed for clinical development by Tesaro, which acts as a selective NK1 receptor antagonist (antagonist for the NK1 receptor). It has been approved as a medication for the treatment of chemotherapy-induced nausea and vomiting (CINV) after clinical trials showed it to have similar or improved efficacy and some improvement in safety over existing drugs for this application.
rdf:langString
rdf:langString
Rolapitant
xsd:integer
51473136
xsd:integer
1102283741
rdf:langString
AD14
rdf:langString
A04
rdf:langString
nearly 100%
xsd:integer
25
xsd:integer
552292
xsd:integer
90908
xsd:integer
8486772
rdf:langString
DB09291
<second>
-658800.0
rdf:langString
Feces , urine
xsd:integer
6
xsd:integer
26
rdf:langString
as HCl
xsd:integer
-8
rdf:langString
D08988
rdf:langString
D10742
rdf:langString
Rx-only
rdf:langString
a615041
xsd:integer
2
xsd:integer
2
rdf:langString
N
xsd:integer
10311306
rdf:langString
By mouth , intravenous
rdf:langString
FCccccc4COCC3NCC1NCCC1
xsd:integer
1
rdf:langString
FIVSJYGQAIEMOC-ZGNKEGEESA-N
rdf:langString
SCH 619734
rdf:langString
Varubi , Varuby
rdf:langString
NLE429IZUC
xsd:integer
225
rdf:langString
Rolapitant (INN, trade name Varubi /vəˈruːbi/ və-ROO-bee in the US and Varuby in the European Union) is a drug originally developed by Schering-Plough and licensed for clinical development by Tesaro, which acts as a selective NK1 receptor antagonist (antagonist for the NK1 receptor). It has been approved as a medication for the treatment of chemotherapy-induced nausea and vomiting (CINV) after clinical trials showed it to have similar or improved efficacy and some improvement in safety over existing drugs for this application.
rdf:langString
Rolapitant
xsd:integer
5749
rdf:langString
Rx-only
rdf:langString
yes
rdf:langString
C4-pyrrolidine-hydroxylated rolapitant
<perCent>
99.8
xsd:nonNegativeInteger
10814
rdf:langString
Varubi (US), Varuby (EU)
xsd:string
552292-08-7
xsd:string
90908
xsd:string
DB09291
xsd:string
NLE429IZUC
xsd:string
D08988
D10742
xsd:string
a615041
xsd:string
10311306
