Resting state fMRI

rdf:langString Resting state fMRI

rdf:langString Resting state fMRI

rdf:langString Movie of the in vivo BOLD signal from the cortical surface of a human subject from HCP, acquired using resting state fMRI, pre-processed to suppress the noise in data and played back at a real-time rate. The BOLD signal intensities are visualized on a smoothed cortical surface. At each point on the cortex, white color represents the average BOLD signal, while blue and red colors represents lower and higher signal than average BOLD signal respectively.

rdf:langString Evaluate regional interactions that occur in resting state

rdf:langString Resting state fMRI (rs-fMRI or R-fMRI) is a method of functional magnetic resonance imaging (fMRI) that is used in brain mapping to evaluate regional interactions that occur in a resting or task-negative state, when an explicit task is not being performed. A number of resting-state brain networks have been identified, one of which is the default mode network. These brain networks are observed through changes in blood flow in the brain which creates what is referred to as a blood-oxygen-level dependent (BOLD) signal that can be measured using fMRI. Because brain activity is intrinsic, present even in the absence of an externally prompted task, any brain region will have spontaneous fluctuations in BOLD signal. The resting state approach is useful to explore the brain's functional organization and to examine if it is altered in neurological or mental disorders. Because of the resting state aspect of this imaging, data can be collected from a range of patient groups including people with intellectual disabilities, pediatric groups, and even those that are unconscious. Resting-state functional connectivity research has revealed a number of networks which are consistently found in healthy subjects, different stages of consciousness and across species, and represent specific patterns of synchronous activity.