Prasterone

http://dbpedia.org/resource/Prasterone an entity of type: Thing

Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand names Intrarosa, Diandrone, and Gynodian Depot among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for childbirth, among other uses. It is taken by mouth, by application to the skin, in through the vagina, or by injection into muscle. rdf:langString
rdf:langString Prasterone
xsd:integer 2998400
xsd:integer 1124604383
rdf:langString XX01
rdf:langString G03
<perCent> 50.0
xsd:integer 19
xsd:integer 53
xsd:integer 28689
xsd:integer 90593
xsd:integer 5670
rdf:langString DB01708
<second> 1500.0 39600.0
xsd:integer 28
rdf:langString Dehydroepiandrosterone molecule ball.png
xsd:integer -3
rdf:langString D08409
rdf:langString Rx-only
rdf:langString a617012
xsd:double 148.5
xsd:integer 2
xsd:integer 5881
rdf:langString By mouth, vaginal , intramuscular , injection
rdf:langString O=C3[C@]2C
xsd:integer 1
rdf:langString FMGSKLZLMKYGDP-USOAJAOKSA-N
rdf:langString EL-10; GL-701; KYH-3102; Androst-5-en-3β-ol-17-one; 3β-Hydroxyandrost-5-en-17-one; 5,6-Didehydroepiandrosterone; Dehydroisoepiandrosterone
rdf:langString background:#ccccff
rdf:langString Intrarosa, others
xsd:integer 459
rdf:langString verified
xsd:integer 443682301
rdf:langString verified
xsd:integer 225 235
rdf:langString Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand names Intrarosa, Diandrone, and Gynodian Depot among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for childbirth, among other uses. It is taken by mouth, by application to the skin, in through the vagina, or by injection into muscle. Side effects of prasterone in women include symptoms of masculinization like oily skin, acne, increased hair growth, voice changes, and increased sexual desire, headaches, insomnia, and others. The compound is a naturally occurring prohormone of androgens and estrogens and hence is an agonist of the androgen and estrogen receptors, the respective biological targets of androgens like testosterone and estrogens like estradiol. Prasterone also has a variety of activities of its own, including neurosteroid and other activities. DHEA, the active ingredient of prasterone, was discovered in 1934. An association between DHEA levels and aging was first reported in 1965. The compound started being used as a medication in the late 1970s and as a supplement in the early 1980s. The marketing of prasterone over-the-counter as a supplement is allowed in the United States but is banned in many other countries.
rdf:langString Prasterone
xsd:integer 2370
rdf:langString S4
rdf:langString Schedule IV
rdf:langString Rx-only
rdf:langString • Estradiol
rdf:langString • Estrone
rdf:langString • sulfate
rdf:langString • Androstanediol
rdf:langString • Androstenediol
rdf:langString • Androstenedione
rdf:langString • Androsterone
rdf:langString • Dihydrotestosterone
rdf:langString • Etiocholanolone
rdf:langString • Testosterone
xsd:float 50.0
xsd:nonNegativeInteger 69401
rdf:langString Intrarosa, others
xsd:string 53-43-0
xsd:string 28689
xsd:string 90593
xsd:string DB01708
xsd:string 459AG36T1B
xsd:string D08409
xsd:string a617012
xsd:string 5881
xsd:string (combination withestrogen)

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