PYR-41

http://dbpedia.org/resource/PYR-41 an entity of type: Thing

PYR-41 is a cell permeable irreversible inhibitor of ubiquitin-activating enzyme E1.It was also reported to increase sumoylation in cells. PYR-41 also blocks the downstream ubiquitination and ubiquitination-dependent protein degradation or other ubiquitination-mediated cellular activities. In addition, PYR-41 inhibits degradation of p53, a tumour suppressor. rdf:langString

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rdf:langString PYR-41

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rdf:langString PYR-41

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rdf:langString PYR-41

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rdf:langString Ethyl 4-{-4-[methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate

dbpedia-owl:abstract

rdf:langString PYR-41 is a cell permeable irreversible inhibitor of ubiquitin-activating enzyme E1.It was also reported to increase sumoylation in cells. PYR-41 also blocks the downstream ubiquitination and ubiquitination-dependent protein degradation or other ubiquitination-mediated cellular activities. In addition, PYR-41 inhibits degradation of p53, a tumour suppressor.

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rdf:langString Ethyl 4-{(4Z)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate

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<http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject>

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<http://www.wikidata.org/entity/Q11173>

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