Nafarelin
http://dbpedia.org/resource/Nafarelin an entity of type: Thing
نافاريلين (بالإنجليزية: Nafarelin) هو دواء يُستعمل في علاج:
* انتباذ بطاني رحمي
rdf:langString
Il nafarelin (conosciuto anche con il nome di nafarelina e D-Nal(2)6-LHRH) è un decapeptide di sintesi, analogo dei fattori di rilascio delle gonadotropine naturali (GnRH) e presenta proprietà simili alla . La sostituzione della glicina in posizione 6 della gonadorelina con una D-naftilalanina aumenta l'idrofobia e rallenta la degradazione enzimatica della nafarelina. La nafarelina viene somministrata in dose singola, come spray nasale, e stimola la secrezione delle gonadotropine ipofisarie, LH e FSH, e di conseguenza stimola la secrezione degli ormoni steroidei delle ovaie e dei testicoli.
rdf:langString
Nafarrelina é um fármaco agonista do hormônio liberador de gonadotrofina (LHRH). Tem utilização na endometriose, fertilização em vitro, puberdade precoce e em terapia hormonal feminizante.
rdf:langString
Nafarelin, sold under the brand name Synarel among others, is a gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in the treatment of endometriosis and early puberty. It is also used to treat uterine fibroids, to control ovarian stimulation in in vitro fertilization (IVF), and as part of transgender hormone therapy. The medication is used as a nasal spray two to three times per day.
rdf:langString
rdf:langString
نافاريلين
rdf:langString
Nafarelin
rdf:langString
Nafarelin
rdf:langString
Nafarrelina
xsd:integer
2102271
xsd:integer
1095366784
rdf:langString
CA02
rdf:langString
H01
rdf:langString
: 2.8%
xsd:integer
66
xsd:integer
76932
xsd:integer
76932
xsd:integer
7445
xsd:integer
1201309
xsd:integer
10482014
rdf:langString
DB00666
<second>
-10800.0
rdf:langString
Feces: 19–44%
rdf:langString
Urine: 44–55%
xsd:integer
83
rdf:langString
-N-[-5-carbamimidamido-1-[-2-[carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[-2-[-2-[-3-hydroxy-2-[-2-[-3--2-{[-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-propanamido]propanamido]-3-propanamido]-3-propanamido]-4-methylpentanamide
rdf:langString
D08241
rdf:langString
Rx-only
rdf:langString
a601082
rdf:langString
Peptidases
xsd:integer
17
xsd:integer
13
rdf:langString
X
xsd:integer
25077649
rdf:langString
CCC[C@H]CN[C@@H]CN1CCC[C@H]1CNCC=O
xsd:integer
1
rdf:langString
RWHUEXWOYVBUCI-ITQXDASVSA-N
rdf:langString
Nafareline; Nafarelin acetate; RS-94991; RS-94991-298; [6-(D)-alanine]-GnRH
rdf:langString
Synarel, others
xsd:integer
1
rdf:langString
verified
xsd:integer
462258124
rdf:langString
verified
xsd:integer
250
rdf:langString
نافاريلين (بالإنجليزية: Nafarelin) هو دواء يُستعمل في علاج:
* انتباذ بطاني رحمي
rdf:langString
Nafarelin, sold under the brand name Synarel among others, is a gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in the treatment of endometriosis and early puberty. It is also used to treat uterine fibroids, to control ovarian stimulation in in vitro fertilization (IVF), and as part of transgender hormone therapy. The medication is used as a nasal spray two to three times per day. Side effects of nafarelin are related to sex hormone deprivation and include symptoms of low testosterone levels and low estrogen levels such as hot flashes, sexual dysfunction, vaginal atrophy, and osteoporosis. Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) and works by preventing the production of sex hormones by the gonads. It can lower sex hormone levels by 95% in both sexes. Nafarelin is a peptide and an analogue of GnRH. Nafarelin was introduced for medical use in 1990. It is available widely throughout the world, including in North America, Europe, and elsewhere throughout the world. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being buserelin.
rdf:langString
Il nafarelin (conosciuto anche con il nome di nafarelina e D-Nal(2)6-LHRH) è un decapeptide di sintesi, analogo dei fattori di rilascio delle gonadotropine naturali (GnRH) e presenta proprietà simili alla . La sostituzione della glicina in posizione 6 della gonadorelina con una D-naftilalanina aumenta l'idrofobia e rallenta la degradazione enzimatica della nafarelina. La nafarelina viene somministrata in dose singola, come spray nasale, e stimola la secrezione delle gonadotropine ipofisarie, LH e FSH, e di conseguenza stimola la secrezione degli ormoni steroidei delle ovaie e dei testicoli.
rdf:langString
Nafarrelina é um fármaco agonista do hormônio liberador de gonadotrofina (LHRH). Tem utilização na endometriose, fertilização em vitro, puberdade precoce e em terapia hormonal feminizante.
xsd:integer
3902
<perCent>
80.0
xsd:nonNegativeInteger
21255
rdf:langString
Synarel, others
xsd:string
76932-56-4
xsd:string
76932-60-0 (acetate)
xsd:string
7445
xsd:string
1201309
xsd:string
DB00666
xsd:string
1X0094V6JV
xsd:string
D08241
xsd:string
a601082
xsd:string
25077649