Mixed lymphocyte reaction
http://dbpedia.org/resource/Mixed_lymphocyte_reaction
Směsná lymfocytární reakce (angl. mixed lymphocyte reaction; MLR) je označení pro laboratorní imunologickou zkoušku. Testuje aloreaktivitu T-lymfocytů dvou jedinců vůči svým antigenům navzájem po jejich přímém rozpoznání, především antigenům hlavního histokompatibilního komplexu (MHC, z angl. major histocompatibility complex. Zkouška bývá součástí rutinních vyšetření v transplantační medicíně.
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La reazione linfocitaria mista è una tecnica di laboratorio per valutare la compatibilità tra un donatore e un ricevente nel caso di trapianti. È infatti noto che i trapianti tra due individui non imparentati (allogenici) hanno un tasso di rigetto molto elevato.Il lungo tempo necessario alla reazione non ne consente l'uso nei trapianti in emergenza, dove si preferisce il test con gli anticorpi anti HLA.
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混合淋巴反应（英語：Mixed Lymphocyte Reaction，简称MLR），也称作混合淋巴细胞培养（MLC），常用于器官移植前的，以测定受体和供体主要组织相容性抗原（HLA抗原）相容的程度。由于MLC中淋巴细胞接受同种异型抗原的刺激而发生活化、增殖，产生种类众多的细胞因子，促进NK、LAK和CTL等杀伤细胞的分化，因此又是免疫调节研究中常用的实验模型。
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Mixed lymphocyte reaction (MLR) is a test used by pharmaceutical and biotech organizations to show the safety of a drug or implantable material. It is commonly used as part of the FDA clearance process. Put simply, it is mixing populations of T-lymphocytes (category of white blood cells) together, and measuring the reaction that occurs. Technically, it is an ex-vivo cellular immune assay that occurs between two allogeneic lymphocyte populations (same species but genetically distinct). In a one-way MLR, only one lymphocyte population can respond or proliferate. In a two-way MLR, both populations can proliferate. MLR’s are performed to assess how T-cells react to external stimuli. T cells are a type of white blood cell that scans for cellular abnormalities and infections. They are essential
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Směsná lymfocytární reakce
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Reazione linfocitaria mista
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Mixed lymphocyte reaction
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混合淋巴反应
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Směsná lymfocytární reakce (angl. mixed lymphocyte reaction; MLR) je označení pro laboratorní imunologickou zkoušku. Testuje aloreaktivitu T-lymfocytů dvou jedinců vůči svým antigenům navzájem po jejich přímém rozpoznání, především antigenům hlavního histokompatibilního komplexu (MHC, z angl. major histocompatibility complex. Zkouška bývá součástí rutinních vyšetření v transplantační medicíně.
rdf:langString
Mixed lymphocyte reaction (MLR) is a test used by pharmaceutical and biotech organizations to show the safety of a drug or implantable material. It is commonly used as part of the FDA clearance process. Put simply, it is mixing populations of T-lymphocytes (category of white blood cells) together, and measuring the reaction that occurs. Technically, it is an ex-vivo cellular immune assay that occurs between two allogeneic lymphocyte populations (same species but genetically distinct). In a one-way MLR, only one lymphocyte population can respond or proliferate. In a two-way MLR, both populations can proliferate. MLR’s are performed to assess how T-cells react to external stimuli. T cells are a type of white blood cell that scans for cellular abnormalities and infections. They are essential to human immunity.
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La reazione linfocitaria mista è una tecnica di laboratorio per valutare la compatibilità tra un donatore e un ricevente nel caso di trapianti. È infatti noto che i trapianti tra due individui non imparentati (allogenici) hanno un tasso di rigetto molto elevato.Il lungo tempo necessario alla reazione non ne consente l'uso nei trapianti in emergenza, dove si preferisce il test con gli anticorpi anti HLA.
rdf:langString
混合淋巴反应（英語：Mixed Lymphocyte Reaction，简称MLR），也称作混合淋巴细胞培养（MLC），常用于器官移植前的，以测定受体和供体主要组织相容性抗原（HLA抗原）相容的程度。由于MLC中淋巴细胞接受同种异型抗原的刺激而发生活化、增殖，产生种类众多的细胞因子，促进NK、LAK和CTL等杀伤细胞的分化，因此又是免疫调节研究中常用的实验模型。
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5503