MS-245

http://dbpedia.org/resource/MS-245 an entity of type: Thing

MS-245 is a tryptamine derivative used in scientific research. It acts as a selective 5-HT6 receptor antagonist with a Ki of 2.3 nM, and was derived through structure-activity relationship development of the selective 5-HT6 agonist EMDT. It has been used as a lead compound for further development of tryptamine-derived 5-HT6 antagonists. In animal studies it has been shown to boost the activity of, but not substitute for, both amphetamine and nicotine. rdf:langString
rdf:langString MS-245
xsd:integer 20009578
xsd:integer 1105894193
rdf:langString none
xsd:integer 19
xsd:integer 263384
xsd:integer 5293739
xsd:integer 22
xsd:integer 2
xsd:integer 2
xsd:integer 3
xsd:integer 6918542
xsd:integer 1
rdf:langString COc2cc1ccnSc3ccccc3
xsd:integer 1
rdf:langString AIJIQCBYMBZLJD-UHFFFAOYSA-N
rdf:langString L7TKH887Y7
xsd:integer 444653781
rdf:langString MS-245 is a tryptamine derivative used in scientific research. It acts as a selective 5-HT6 receptor antagonist with a Ki of 2.3 nM, and was derived through structure-activity relationship development of the selective 5-HT6 agonist EMDT. It has been used as a lead compound for further development of tryptamine-derived 5-HT6 antagonists. In animal studies it has been shown to boost the activity of, but not substitute for, both amphetamine and nicotine.
xsd:nonNegativeInteger 3722
xsd:string 263384-65-2
xsd:string L7TKH887Y7
xsd:string 6918542

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