Ka/Ks ratio
http://dbpedia.org/resource/Ka/Ks_ratio an entity of type: ChemicalCompound
In der Genetik dient das Ka/Ks-Verhältnis (auch dN/dS-Verhältnis oder ω genannt) um innerhalb einer Sequenz eines Gens zwischen neutralen, negativ selektierenden oder positiv selektierenden Mutationen unterscheiden zu können. Es berechnet sich aus den sogenannten nicht synonymen Substitutionen und den synonymen Substitutionen.
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在遗传学中，Ka/Ks或者dN/dS表示的是（Ka）和（Ks）之间的比例。这个比例可以判断是否有选择压力作用于这个蛋白质编码基因。异义替换导致氨基酸的改变，而同义替换由于密码子虽然改变，但是仍旧对应的是同一氨基酸。 由于异义替换往往对于生命体有害，所以在的作用下，异义替换常常会在群体中被逐渐消灭。
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In genetics, the Ka/Ks ratio, also known as ω or dN/dS ratio, is used to estimate the balance between neutral mutations, purifying selection and beneficial mutations acting on a set of homologous protein-coding genes. It is calculated as the ratio of the number of nonsynonymous substitutions per non-synonymous site (Ka), in a given period of time, to the number of synonymous substitutions per synonymous site (Ks), in the same period. The latter are assumed to be neutral, so that the ratio indicates the net balance between deleterious and beneficial mutations. Values of Ka/Ks significantly above 1 are unlikely to occur without at least some of the mutations being advantageous. If beneficial mutations are assumed to make little contribution, then Ka/Ks estimates the degree of evolutionary co
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Ka/Ks-Verhältnis
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Ka/Ks ratio
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Ka/Ks
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5457540
xsd:integer
1118754446
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In der Genetik dient das Ka/Ks-Verhältnis (auch dN/dS-Verhältnis oder ω genannt) um innerhalb einer Sequenz eines Gens zwischen neutralen, negativ selektierenden oder positiv selektierenden Mutationen unterscheiden zu können. Es berechnet sich aus den sogenannten nicht synonymen Substitutionen und den synonymen Substitutionen.
rdf:langString
In genetics, the Ka/Ks ratio, also known as ω or dN/dS ratio, is used to estimate the balance between neutral mutations, purifying selection and beneficial mutations acting on a set of homologous protein-coding genes. It is calculated as the ratio of the number of nonsynonymous substitutions per non-synonymous site (Ka), in a given period of time, to the number of synonymous substitutions per synonymous site (Ks), in the same period. The latter are assumed to be neutral, so that the ratio indicates the net balance between deleterious and beneficial mutations. Values of Ka/Ks significantly above 1 are unlikely to occur without at least some of the mutations being advantageous. If beneficial mutations are assumed to make little contribution, then Ka/Ks estimates the degree of evolutionary constraint.
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在遗传学中，Ka/Ks或者dN/dS表示的是（Ka）和（Ks）之间的比例。这个比例可以判断是否有选择压力作用于这个蛋白质编码基因。异义替换导致氨基酸的改变，而同义替换由于密码子虽然改变，但是仍旧对应的是同一氨基酸。 由于异义替换往往对于生命体有害，所以在的作用下，异义替换常常会在群体中被逐渐消灭。
xsd:nonNegativeInteger
23234