Interleukin-17 receptor
http://dbpedia.org/resource/Interleukin-17_receptor an entity of type: Thing
Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a member of IL-17 family ligands produced by T helper 17 cells (Th17). IL-17R family consists of 5 members: IL-17RA, IL-17RB, IL-17RC, IL-17RD and . Functional IL-17R is a transmembrane receptor complex usually consisting of one IL-17RA, which is a founding member of the family, and second other family subunit, thus forming heteromeric receptor binding different ligands. IL-17A, a founding member of IL-17 ligand family binds to heteromeric IL-17RA/RC receptor complex. IL-17RB binds preferentially IL-17B and IL-17E and heteromeric IL-17RA/RE complex binds IL-17C. However, there is still unknown ligand for IL-17RD. The first identified member I
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Interleukin-17 receptor
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Interleukin 17 receptor D
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Interleukin 17 receptor E-like
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interleukin 17 receptor A
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interleukin 17 receptor B
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interleukin 17 receptor C
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interleukin 17 receptor E
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Interleukin-17 receptor
xsd:integer
16036908
xsd:integer
1121534687
xsd:integer
605458
605461
606807
610925
rdf:langString
FLJ23658
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IL17-RL
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IL17BR
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IL17R, CDw217
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SEF, IL17RLM, FLJ35755, IL-17RD
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Crystal structure of a complex of IL-17RA bound to IL-17F in a 1:2 stoichiometry.
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IPR013568
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PF08357
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IL17R
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IL17RD
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IL17RE
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IL17REL
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Q6ZVW7
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Q8NAC3
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Q8NFM7
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Q8NFR9
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Q96F46
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Q9NRM6
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Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a member of IL-17 family ligands produced by T helper 17 cells (Th17). IL-17R family consists of 5 members: IL-17RA, IL-17RB, IL-17RC, IL-17RD and . Functional IL-17R is a transmembrane receptor complex usually consisting of one IL-17RA, which is a founding member of the family, and second other family subunit, thus forming heteromeric receptor binding different ligands. IL-17A, a founding member of IL-17 ligand family binds to heteromeric IL-17RA/RC receptor complex. IL-17RB binds preferentially IL-17B and IL-17E and heteromeric IL-17RA/RE complex binds IL-17C. However, there is still unknown ligand for IL-17RD. The first identified member IL-17RA is located on human chromosome 22, whereas other subunits IL-17RB to IL-17RD are encoded within human chromosome 3.
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p
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q
xsd:double
11.1
13.33
21.1
25.3
xsd:integer
3
22
xsd:integer
23765
54756
55540
84818
132014
400935
xsd:integer
5985
17616
18015
18358
18439
33808
xsd:integer
8
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NM_001001694
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NM_014339
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NM_017563
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NM_032732
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NM_153480
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NM_172234
xsd:string
p
q
xsd:string
21.1
25.3
11.1
13.33
xsd:string
3
22
xsd:string
132014
23765
400935
54756
55540
84818
xsd:string
18015
5985
17616
18358
18439
33808
xsd:string
NM_001001694
xsd:string
NM_014339
xsd:string
NM_017563
xsd:string
NM_032732
xsd:string
NM_153480
xsd:string
NM_172234
xsd:string
Q6ZVW7
Q8NAC3
Q8NFM7
Q8NFR9
Q96F46
Q9NRM6
xsd:nonNegativeInteger
20855
xsd:integer
605458
605461
606807
610925
xsd:string
FLJ23658
xsd:string
IL17-RL
xsd:string
IL17BR
xsd:string
IL17R
xsd:string
IL17R, CDw217
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IL17RA
xsd:string
IL17RB
xsd:string
IL17RC
xsd:string
IL17RD
xsd:string
IL17RE
xsd:string
IL17REL
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SEF, IL17RLM, FLJ35755, IL-17RD