Indatraline
http://dbpedia.org/resource/Indatraline an entity of type: Thing
Indatraline (Lu 19-005) is a non-selective monoamine transporter inhibitor shown to block the reuptake of dopamine, norepinephrine, and serotonin, with effects similar to those of cocaine. The effects have been shown to have a slower onset and longer duration than cocaine, suggesting that the compound may, along with similar compounds, be used for the treatment of cocaine addiction. LU 19-005 has been shown to block the action of methamphetamine and MDMA in laboratory experiments.
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Indatraline
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April 2022
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The cited article does not mention superposition directly; this may indicate independent synthesis of the data
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Oral
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Clc1ccc[C@@H]3C[C@H]c2ccccc23
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Indatraline (Lu 19-005) is a non-selective monoamine transporter inhibitor shown to block the reuptake of dopamine, norepinephrine, and serotonin, with effects similar to those of cocaine. The effects have been shown to have a slower onset and longer duration than cocaine, suggesting that the compound may, along with similar compounds, be used for the treatment of cocaine addiction. LU 19-005 has been shown to block the action of methamphetamine and MDMA in laboratory experiments. Superposition should make it possible to see there is at least a fundamental relationship between the pharmacophore of indatraline and various phenyltropanes.
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