Heparan sulfate 2-O-sulfotransferase
http://dbpedia.org/resource/Heparan_sulfate_2-O-sulfotransferase an entity of type: Thing
Heparan sulfate 2-O-sulfotransferase is a sulfotransferase enzyme. Heparan sulfate (HS) is a long unbranched polysaccharide found covalently attached to various proteins at the cell surface and in the extracellular matrix, where it acts as a co-receptor for a number of growth factors, , and adhesion proteins. HS-O-sulfotransferase (Hs2st) occupies a critical position in the succession of enzymes responsible for the biosynthesis of HS, catalysing the transfer of sulfate to the C2-position of selected hexuronic acid residues within the nascent HS chain. Mice that lack HS2ST undergo developmental failure after , the most dramatic effect being the complete failure of kidney development. This family is related to InterPro: IPR005331.
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Heparan sulfate 2-O-sulfotransferase
rdf:langString
Heparan sulfate 2-O-sulfotransferase
xsd:integer
29199716
xsd:integer
977870516
rdf:langString
IPR005331
rdf:langString
PF03567
rdf:langString
HS2ST
rdf:langString
Heparan sulfate 2-O-sulfotransferase is a sulfotransferase enzyme. Heparan sulfate (HS) is a long unbranched polysaccharide found covalently attached to various proteins at the cell surface and in the extracellular matrix, where it acts as a co-receptor for a number of growth factors, , and adhesion proteins. HS-O-sulfotransferase (Hs2st) occupies a critical position in the succession of enzymes responsible for the biosynthesis of HS, catalysing the transfer of sulfate to the C2-position of selected hexuronic acid residues within the nascent HS chain. Mice that lack HS2ST undergo developmental failure after , the most dramatic effect being the complete failure of kidney development. This family is related to InterPro: IPR005331.
xsd:nonNegativeInteger
1445
xsd:string
HS2ST