H antigen

rdf:langString H antigen

rdf:langString H antigen can refer to one of various types of antigens having diverse biological functions. H antigen is located on the 19th chromosome in humans, and has a variety of functions and definitions as follows: * Also known as substance H, H antigen is a precursor to each of the ABO blood group antigens, apparently present in all people except those with the Bombay Blood phenotype (see hh blood group) * Histocompatibility antigen, a major factor in graft rejection. Even when Major Histocompatibility Complex genotype is perfectly matched, can cause slow rejection of a graft. * major H antigens "encode molecules that present foreign peptides to T cells" * minor H antigens "present polymorphic self peptides to T cells". Includes, e.g. the H-Y antigen * a bacterial flagellar antigen