Gastruloid

Gastruloids are three dimensional aggregates of embryonic stem cells (ESCs) that, under appropriate culture conditions, develop an embryo-like organization with three orthogonal axes and a precise distribution of the primordia for multiple derivatives of the three germ layers in the absence of extraembryonic tissues. Significantly, they lack fore- mid- and hindbrain. They are a model system an embryonic organoid for the study of mammalian development (including humans) and disease. rdf:langString