Eugeroic
http://dbpedia.org/resource/Eugeroic
Eugeroics (originally "eugrégorique" or "eugregoric"), also known as wakefulness-promoting agents and wakefulness-promoting drugs, are a class of drugs that promote wakefulness and alertness. They are medically indicated for the treatment of certain sleep disorders including excessive daytime sleepiness (EDS) in narcolepsy or obstructive sleep apnea (OSA). Eugeroics are also often prescribed off-label for the treatment of EDS in idiopathic hypersomnia, a rare and often debilitating sleep disorder which currently has no official treatments approved by the Food and Drug Administration (FDA). In contrast to classical psychostimulants, such as methylphenidate and amphetamine, which are also used in the treatment of these disorders, eugeroics typically do not produce euphoria, and, consequently
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Eugeroico (del inglés eugeroic) o agente que promueve la vigilia (Wakefulness-promoting agent). Un eugeroico es un compuesto que favorece el estado de vigilia y alerta, reduciendo fatiga y somnolencia. Se usan en el tratamiento de desórdenes del sueño, somnolencia diurna excesiva y narcolepsia, aunque como nootrópicos son usados para contrarrestar fatiga, aumentando motivación y productividad o simplemente para mantener la vigilia.
* Datos: Q7961095
* Multimedia: Eugeroics / Q7961095
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I farmaci stimolanti la vigilanza, noti anche come eugeroici (in origine eugrégorique o eugregoric), è un tipo di farmaco che migliora specificamente la veglia e la vigilanza. Essi sono utilizzati principalmente nel trattamento dei disturbi del sonno, eccessiva sonnolenza diurna e narcolessia. Essi sono utilizzati anche per contrastare la stanchezza e la letargia e per aumentare la motivazione e la produttività.
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Eugeroico
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Eugeroic
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Farmaci stimolanti la vigilanza
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23857598
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1112362796
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N06B
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The chemical structure of modafinil, the prototypical drug of this class.
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wakefulness-promoting agent
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wakefulness-promoting drug
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Promote wakefulness and alertness
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Eugeroics (originally "eugrégorique" or "eugregoric"), also known as wakefulness-promoting agents and wakefulness-promoting drugs, are a class of drugs that promote wakefulness and alertness. They are medically indicated for the treatment of certain sleep disorders including excessive daytime sleepiness (EDS) in narcolepsy or obstructive sleep apnea (OSA). Eugeroics are also often prescribed off-label for the treatment of EDS in idiopathic hypersomnia, a rare and often debilitating sleep disorder which currently has no official treatments approved by the Food and Drug Administration (FDA). In contrast to classical psychostimulants, such as methylphenidate and amphetamine, which are also used in the treatment of these disorders, eugeroics typically do not produce euphoria, and, consequently, have a lower addictive potential. Modafinil and armodafinil are each thought to act as selective, weak, atypical dopamine reuptake inhibitors (DRI), whereas adrafinil acts as a prodrug for modafinil. Other eugeroics include solriamfetol, which acts as a norepinephrine–dopamine reuptake inhibitor (NDRI), and pitolisant, which acts as a histamine 3 (H3) receptor antagonist/inverse agonist.
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Eugeroico (del inglés eugeroic) o agente que promueve la vigilia (Wakefulness-promoting agent). Un eugeroico es un compuesto que favorece el estado de vigilia y alerta, reduciendo fatiga y somnolencia. Se usan en el tratamiento de desórdenes del sueño, somnolencia diurna excesiva y narcolepsia, aunque como nootrópicos son usados para contrarrestar fatiga, aumentando motivación y productividad o simplemente para mantener la vigilia. Los eugeroicos actúan aumentando la actividad del sistema adrenérgico, dopaminérgico, histaminérgico y orexinérgico (hipocreatinas)(2). A diferencia de otros estimulantes no causan dependencia y son raramente adictivos. Un eugeroico se considera un estimulante de acción prolongada. La diferencia entre los eugeroicos con estimulantes cómo anfetamina y metilfenidato es que mientras estos producen una excitación difusa en el cerebro, un eugeroico actúa de manera localizada en el hipotálamo, en el que reside el control de la vigilia (1,2). El prototipo de eugeroico es el modafinilo, así como la variedad armodafinilo y el derivado adrafinilo.
* Datos: Q7961095
* Multimedia: Eugeroics / Q7961095
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I farmaci stimolanti la vigilanza, noti anche come eugeroici (in origine eugrégorique o eugregoric), è un tipo di farmaco che migliora specificamente la veglia e la vigilanza. Essi sono utilizzati principalmente nel trattamento dei disturbi del sonno, eccessiva sonnolenza diurna e narcolessia. Essi sono utilizzati anche per contrastare la stanchezza e la letargia e per aumentare la motivazione e la produttività. Il prototipo eugeroico è il modafinil, altri farmaci comprendono l'adrafinil e l'armodafinil. Modafinil e armodafinil sembrano agire come deboli inibitori atipici della ricaptazione della dopamina. Adrafinil è un profarmaco del modafinil, e quindi agisce anche in modo simile.
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8240