Estriol (medication)
http://dbpedia.org/resource/Estriol_(medication) an entity of type: Thing
Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs. The medication is taken by mouth in the form of tablets, as a cream that is applied to the skin, as a cream or pessary that is applied in the vagina, and by injection into muscle.
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rdf:langString
Estriol (medication)
xsd:integer
56981867
xsd:integer
1109028233
xsd:double
0.119
rdf:langString
CA04
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right
rdf:langString
G03
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Oral: ~1–2%
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Vaginal: ~10–20%
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18
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Note the hydroxyl groups: estrone has one, estradiol has two, estriol has three, and estetrol has four.
xsd:integer
50
xsd:integer
514
xsd:date
1306-04-03
xsd:integer
27974
xsd:integer
193482
xsd:integer
5553
rdf:langString
DB04573
<second>
-36000.0
1200.0
-19080.0
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Urine: >95%
xsd:integer
24
rdf:langString
Estriol molecule ball.png
xsd:integer
-13
<nicaraguanCórdoba>
5141.0
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Rx-only
xsd:integer
86
xsd:integer
82
rdf:langString
Liver, intestines
xsd:integer
3
xsd:integer
5756
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Oc1cc3c[C@H]2CC[C@@]4C
xsd:integer
1
rdf:langString
PROQIPRRNZUXQM-ZXXIGWHRSA-N
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Oestriol; E3; 16α-Hydroxyestradiol; Estra-1,3,5-triene-3,16α,17β-triol
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Ovestin, others
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FB33469R8E
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verified
xsd:integer
477167082
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verified
xsd:integer
235
250
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Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs. The medication is taken by mouth in the form of tablets, as a cream that is applied to the skin, as a cream or pessary that is applied in the vagina, and by injection into muscle. Estriol is well-tolerated and produces relatively few adverse effects. Side effects may include breast tenderness, vaginal discomfort and discharge, and endometrial hyperplasia. Estriol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. It is an atypical and relatively weak estrogen, with much lower potency than estradiol. When present continuously at adequate concentrations however, estriol produces full estrogenic effects similarly to estradiol. Estriol was first discovered in 1930, and was introduced for medical use shortly thereafter. Estriol esters such as estriol succinate are also used. Although it is less commonly employed than other estrogens like estradiol and conjugated estrogens, estriol is widely available for medical use in Europe and elsewhere throughout the world.
xsd:integer
2821
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• Others
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• 16α-Hydroxyestrone
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• Estriol 16α-glucuronide
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• Estriol 3-glucuronide
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• Estriol 3-sulfate
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• Estriol 3-sulfate 16α-gluc.
xsd:integer
92
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• : 1%
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• Albumin: 91%
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• Free: 8%
xsd:nonNegativeInteger
79534
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Ovestin, others
xsd:string
1306-04-3
xsd:string
50-27-1
xsd:string
514-68-1 (succinate)
xsd:string
27974
xsd:string
193482
xsd:string
DB04573
xsd:string
FB33469R8E
xsd:string
C05141
xsd:string
5756
