DPA-713
http://dbpedia.org/resource/DPA-713 an entity of type: Thing
DPA-713 or N,N-diethyl-2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide is a selective ligand for the translocator protein (TSPO). The binding affinity of DPA-713 for TSPO is reported as Ki = 4.7 ± 0.2 nM. DPA-713 has been radiolabelled with carbon-11 as a potential radiotracer for imaging the TSPO using positron emission tomography (PET). Radiation dosimetry and biodistribution of [11C]DPA-713 have been assessed in healthy volunteers, indicating that [11C]DPA-713 is a suitable for imaging the TSPO in humans.
rdf:langString
rdf:langString
DPA-713
xsd:integer
36123235
xsd:integer
994935685
xsd:integer
21
xsd:integer
386297
xsd:integer
9770519
xsd:integer
26
rdf:langString
N,N-diethyl-2--5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide
xsd:integer
4
xsd:integer
2
xsd:integer
11595759
rdf:langString
CCNCCC1=C2N=CC
xsd:integer
1
rdf:langString
ILZWUAWCTNWSFZ-UHFFFAOYSA-N
rdf:langString
PQF723MLIV
rdf:langString
DPA-713 or N,N-diethyl-2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide is a selective ligand for the translocator protein (TSPO). The binding affinity of DPA-713 for TSPO is reported as Ki = 4.7 ± 0.2 nM. DPA-713 has been radiolabelled with carbon-11 as a potential radiotracer for imaging the TSPO using positron emission tomography (PET). Radiation dosimetry and biodistribution of [11C]DPA-713 have been assessed in healthy volunteers, indicating that [11C]DPA-713 is a suitable for imaging the TSPO in humans.
xsd:nonNegativeInteger
5218
xsd:string
386297-97-8
xsd:string
PQF723MLIV
xsd:string
11595759