DNA/RNA non-specific endonuclease

http://dbpedia.org/resource/DNA/RNA_non-specific_endonuclease an entity of type: Thing

In molecular biology, enzymes in the DNA/RNA non-specific endonuclease family of bacterial and eukaryotic endonucleases EC 3.1.30.- share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. A histidine has been shown to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion. rdf:langString
rdf:langString DNA/RNA non-specific endonuclease
rdf:langString Endonuclease_NS
xsd:integer 32688500
xsd:integer 995797661
rdf:langString PDOC00821
xsd:integer 1
rdf:langString identification of the serratia endonuclease dimer: structural basis and implications for catalysis
rdf:langString IPR001604
rdf:langString PF01223
rdf:langString CL0263
rdf:langString Endonuclease_NS
rdf:langString In molecular biology, enzymes in the DNA/RNA non-specific endonuclease family of bacterial and eukaryotic endonucleases EC 3.1.30.- share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. A histidine has been shown to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion. Notable members of the family include Serratia marcescens NucA and human .
rdf:langString cd00091
xsd:nonNegativeInteger 1796
xsd:string Endonuclease_NS

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