Crizanlizumab

http://dbpedia.org/resource/Crizanlizumab an entity of type: Thing

Кризанлизумаб — моноклональное антитело для лечения серповидноклеточной анемии. Одобрен для применения: США (ноябрь 2019). rdf:langString
Crizanlizumab, sold under the brand name Adakveo & Ryverna both by Novartis, is a monoclonal antibody medication that binds to P-selectin. It is a drug used to reduce the frequency of vaso-occlusive crisis in people aged 16 years and older who have sickle cell anemia. Vaso-occlusive crisis is a common and painful complication of sickle cell disease that occurs when blood circulation is obstructed by sickled red blood cells (red cells are usually round and flexible, but sometimes many red cells in a person with sickle cell anemia will become rigid and crescent-shaped due to polymerization of hemoglobin). rdf:langString
rdf:langString Crizanlizumab
rdf:langString Кризанлизумаб
xsd:integer 52481577
xsd:integer 1090917138
rdf:langString AX01
rdf:langString B06
xsd:integer 6458
xsd:integer 1690318
rdf:langString none
rdf:langString DB15271
xsd:integer 9948
rdf:langString D11480
rdf:langString Rx-only
rdf:langString a620010
xsd:integer 1712
xsd:integer 2050
xsd:integer 58
rdf:langString zu
rdf:langString SEG101, SelG1, crizanlizumab-tmca
rdf:langString Adakveo
rdf:langString mab
rdf:langString L7451S9126
rdf:langString Crizanlizumab, sold under the brand name Adakveo & Ryverna both by Novartis, is a monoclonal antibody medication that binds to P-selectin. It is a drug used to reduce the frequency of vaso-occlusive crisis in people aged 16 years and older who have sickle cell anemia. Vaso-occlusive crisis is a common and painful complication of sickle cell disease that occurs when blood circulation is obstructed by sickled red blood cells (red cells are usually round and flexible, but sometimes many red cells in a person with sickle cell anemia will become rigid and crescent-shaped due to polymerization of hemoglobin). The result of the Phase II SUSTAIN clinical trial was published in December 2016, and in November 2019, crizanlizumab-tmca was approved in the United States. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.
rdf:langString Кризанлизумаб — моноклональное антитело для лечения серповидноклеточной анемии. Одобрен для применения: США (ноябрь 2019).
rdf:langString Crizanlizumab
rdf:langString S4
rdf:langString Rx-only
rdf:langString Adakveo
rdf:langString mab
rdf:langString B1
xsd:nonNegativeInteger 8998
rdf:langString Adakveo
xsd:string 1690318-25-2
xsd:string DB15271
xsd:string L7451S9126
xsd:string D11480
xsd:string a620010

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