Collybistin
http://dbpedia.org/resource/Collybistin an entity of type: Artifact100021939
Collybistin is a protein identified as a regulator of the localization of gephyrin, inducing the formation of gephyrin aggregates that accumulate glycine and GABA receptors. In 2000 it was identified as a gephyrin binding partner, and an important determinant of inhibitory postsynaptic membrane formation and plasticity. Gephyrin and collybistin are recruited to developing postsynaptic membranes of inhibitory synapses by the trans-synaptic adhesion molecule neuroligin-2, where they provide the scaffold for the clustering of inhibitory postsynaptic receptors to form a functioning inhibitory synapse.
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Collybistin
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21132645
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1116604085
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Collybistin is a protein identified as a regulator of the localization of gephyrin, inducing the formation of gephyrin aggregates that accumulate glycine and GABA receptors. In 2000 it was identified as a gephyrin binding partner, and an important determinant of inhibitory postsynaptic membrane formation and plasticity. Gephyrin and collybistin are recruited to developing postsynaptic membranes of inhibitory synapses by the trans-synaptic adhesion molecule neuroligin-2, where they provide the scaffold for the clustering of inhibitory postsynaptic receptors to form a functioning inhibitory synapse.
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2015