CD32
http://dbpedia.org/resource/CD32 an entity of type: Thing
CD32 هوَ بروتين يُشَفر بواسطة جين CD32 في الإنسان.
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Il CD32 è una glicoproteina di membrana presente sui linfociti B e sui macrofagi. Il suo nome FCγRII è indicativo della sua funzione ovvero recettore per la parte costante delle immunoglobuline di tipo γ con affinità intermedia (mentre ha affinità alta e bassa).
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CD32 (cluster of differentiation 32), also known as FcγRII or FCGR2, is a surface receptor glycoprotein belonging to the Ig gene superfamily. CD32 can be found on the surface of a variety of immune cells. CD32 has a low-affinity for the Fc region of IgG antibodies in monomeric form, but high affinity for IgG immune complexes. CD32 has two major functions: cellular response regulation, and the uptake of immune complexes. Cellular responses regulated by CD32 include phagocytosis, cytokine stimulation, and endocytic transport. Dysregulated CD32 is associated with different forms of autoimmunity, including systemic lupus erythematosus. In humans, there are three major CD32 subtypes: CD32A, CD32B, and CD32C. While CD32A and CD32C are involved in activating cellular responses, CD32B is inhibitor
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CD32
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CD32
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CD32 (proteina)
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Fc fragment of IgG, low affinity IIc, receptor for (CD32)
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Fc fragment of IgG, low affinity IIb, receptor (CD32)
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Fc fragment of IgG, low affinity IIa, receptor (CD32)
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Fc fragment of IgG, low affinity IIc, receptor for
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245408
xsd:integer
1114390846
xsd:integer
146790
604590
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FCG2, FCGR2
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FCG2, FCGR2A1, FCGR2
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Crystal structure of the human fcgamma-receptor IIb ectodomain .
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FCGR2C
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P12318
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P31994
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P31995
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CD32 هوَ بروتين يُشَفر بواسطة جين CD32 في الإنسان.
rdf:langString
CD32 (cluster of differentiation 32), also known as FcγRII or FCGR2, is a surface receptor glycoprotein belonging to the Ig gene superfamily. CD32 can be found on the surface of a variety of immune cells. CD32 has a low-affinity for the Fc region of IgG antibodies in monomeric form, but high affinity for IgG immune complexes. CD32 has two major functions: cellular response regulation, and the uptake of immune complexes. Cellular responses regulated by CD32 include phagocytosis, cytokine stimulation, and endocytic transport. Dysregulated CD32 is associated with different forms of autoimmunity, including systemic lupus erythematosus. In humans, there are three major CD32 subtypes: CD32A, CD32B, and CD32C. While CD32A and CD32C are involved in activating cellular responses, CD32B is inhibitory.
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Il CD32 è una glicoproteina di membrana presente sui linfociti B e sui macrofagi. Il suo nome FCγRII è indicativo della sua funzione ovvero recettore per la parte costante delle immunoglobuline di tipo γ con affinità intermedia (mentre ha affinità alta e bassa).
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q
xsd:integer
23
xsd:integer
1
xsd:integer
2212
2213
9103
xsd:integer
3616
3618
15626
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NM_004001
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NM_021642
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NM_201563
xsd:string
q
xsd:string
23
xsd:string
1
xsd:string
9103
2212
2213
xsd:string
15626
3616
3618
xsd:string
NM_004001
xsd:string
NM_021642
xsd:string
NM_201563
xsd:string
P12318
P31994
P31995
xsd:nonNegativeInteger
11034
xsd:integer
146790
604590
xsd:string
FCG2, FCGR2
xsd:string
FCG2, FCGR2A1, FCGR2
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FCGR2A
xsd:string
FCGR2B
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FCGR2C