Buserelin
http://dbpedia.org/resource/Buserelin an entity of type: Thing
Buserelin ist die Abkürzung für Butylserylrelin und beschreibt einen hormonell wirksamen Arzneistoff, der als GnRH-Analogon wirkt.
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La buserelina è un ormone di rilascio delle gonadotropine ed è un agonista del GnRH. Il buserelin acetato è commercializzato da Sanofi-Aventis con il marchio Suprefact ma è anche disponibile il generico.
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Buserelina é um fármaco. Promove a estimulação da produção do hormônio luteinizante (LH) e do hormônio folículo-estimulante (FSH). É utilizado como anticoncepcional, na endometriose e no carcinoma de próstata.
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Buserelinacetat är det vanligaste medlet i den grupp läkemedel som på engelska kallas Gonadotropin releasing hormone analogue, GnRH-analoger. I Sverige säljs buserelinacetet under handelsnamnet Receptal (veterinärmedicinskt) respektive Suprefact (medicinskt). Medlen är syntetiska peptidpreparat utformade med hormonet GnRH, som utsöndras från hypotalamus, som modell. Dess främsta användningsområde hos människor är som behandling vid prostatacancer, då medlet minskar testosteronhalten hos män.
rdf:langString
Бусерелін (англ. Buserelin, лат. Buserelinum) — синтетичний лікарський препарат, який за своєю хімічною будовою є поліпептидом та аналогом гонадотропін-рилізинг гормону, та застосовується як перорально, так і внутрішньом'язово, підшкірно та внутрішньовенно, а також інтраназально. Бусерелін синтезований у 1976 році, та застосовується у клінічній практиці з 1984 року.
rdf:langString
Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis. It is also used for other indications such as the treatment of premenopausal breast cancer, uterine fibroids, and early puberty, in assisted reproduction for female infertility, and as a part of transgender hormone therapy. In addition, buserelin is used in veterinary medicine. The medication is typically used as a nasal spray three times per day, but is also available for use as a solution or implant for injection into fat.
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rdf:langString
Buserelin
rdf:langString
Buserelin
rdf:langString
Buserelina
rdf:langString
Buserelina
rdf:langString
Бусерелін
rdf:langString
Buserelinacetat
xsd:integer
2102388
xsd:integer
1093081712
rdf:langString
AE01
rdf:langString
L02
rdf:langString
Intranasal: 2.5–3.3%
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Oral: ineffective
rdf:langString
Subcutaneous: 70%
xsd:integer
60
xsd:integer
57982
xsd:integer
68630
xsd:integer
135907
xsd:integer
2110824
xsd:integer
45545
rdf:langString
DB06719
<second>
4800.0
-7200.0
-4800.0
xsd:integer
86
rdf:langString
Buserelin molecule ball.png
rdf:langString
-N-[-1-[[-1-[[-1-[[-1-[[-1-[[-1-[[-5--1-[-2-pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[oxy]-1-oxopropan-2-yl]amino]-3--1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3--1-oxopropan-2-yl]amino]-3--1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
rdf:langString
Rx-only
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Liver, kidneys, gastrointestinal tract
xsd:integer
16
xsd:integer
13
rdf:langString
X
xsd:integer
50225
rdf:langString
CCNC[C@@H]1CCCN1C[C@H]NC[C@H]NC[C@@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@@H]6CCCN6
xsd:integer
1
rdf:langString
CUWODFFVMXJOKD-UVLQAERKSA-N
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Etilamide; HOE-766; HOE-766A; ICI-123215; S-746766; (D)-Ser6EA10-LHRH; 6-[O--(D)-serine]-9--10-deglycinamide-LHRH
rdf:langString
Suprefact, others
rdf:langString
PXW8U3YXDV
rdf:langString
verified
xsd:integer
477165149
rdf:langString
verified
xsd:integer
225
235
rdf:langString
Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis. It is also used for other indications such as the treatment of premenopausal breast cancer, uterine fibroids, and early puberty, in assisted reproduction for female infertility, and as a part of transgender hormone therapy. In addition, buserelin is used in veterinary medicine. The medication is typically used as a nasal spray three times per day, but is also available for use as a solution or implant for injection into fat. Side effects of buserelin are related to sex hormone deprivation and include symptoms of low testosterone levels and low estrogen levels such as hot flashes, sexual dysfunction, vaginal atrophy, and osteoporosis. Buserelin is a gonadotropin-releasing hormone agonist (GnRH agonist) and works by preventing the production of sex hormones by the gonads. It can lower sex hormone levels by about 95% in both sexes. Buserelin is a peptide and an analogue of GnRH. Buserelin was first patented in 1974 and approved for medical use in 1985. It is not available in the United States, but is marketed widely elsewhere in the world, including in the United Kingdom, Canada, and many other countries. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being nafarelin. Buserelin is available as a generic medication.
rdf:langString
Buserelin ist die Abkürzung für Butylserylrelin und beschreibt einen hormonell wirksamen Arzneistoff, der als GnRH-Analogon wirkt.
rdf:langString
La buserelina è un ormone di rilascio delle gonadotropine ed è un agonista del GnRH. Il buserelin acetato è commercializzato da Sanofi-Aventis con il marchio Suprefact ma è anche disponibile il generico.
rdf:langString
Buserelina é um fármaco. Promove a estimulação da produção do hormônio luteinizante (LH) e do hormônio folículo-estimulante (FSH). É utilizado como anticoncepcional, na endometriose e no carcinoma de próstata.
rdf:langString
Buserelinacetat är det vanligaste medlet i den grupp läkemedel som på engelska kallas Gonadotropin releasing hormone analogue, GnRH-analoger. I Sverige säljs buserelinacetet under handelsnamnet Receptal (veterinärmedicinskt) respektive Suprefact (medicinskt). Medlen är syntetiska peptidpreparat utformade med hormonet GnRH, som utsöndras från hypotalamus, som modell. Dess främsta användningsområde hos människor är som behandling vid prostatacancer, då medlet minskar testosteronhalten hos män.
rdf:langString
Бусерелін (англ. Buserelin, лат. Buserelinum) — синтетичний лікарський препарат, який за своєю хімічною будовою є поліпептидом та аналогом гонадотропін-рилізинг гормону, та застосовується як перорально, так і внутрішньом'язово, підшкірно та внутрішньовенно, а також інтраназально. Бусерелін синтезований у 1976 році, та застосовується у клінічній практиці з 1984 року.
xsd:integer
3860
rdf:langString
Buserelin
<perCent>
15.0
xsd:nonNegativeInteger
35430
rdf:langString
Suprefact, others
xsd:string
57982-77-1
xsd:string
68630-75-1 (acetate)
xsd:string
135907
xsd:string
2110824
xsd:string
DB06719
xsd:string
PXW8U3YXDV
xsd:string
50225