BOSC23
http://dbpedia.org/resource/BOSC23 an entity of type: WikicatCellLines
BOSC23是衍生自293T細胞系的人類腎細胞系，由沃倫·皮爾（Warren Pear）在戴維·巴爾的摩的實驗室中開發。BOSC23的主要用途是製造重組逆轉錄病毒。它穩定表達蛋白。當用重組反轉錄病毒載體DNA瞬時轉染時，會產生高滴度的感染性反轉錄病毒顆粒。該細胞不會產生具有複製能力的病毒，這是一項重要的安全功能。BOSC23具有源自其親本系293T的新黴素/ 遺傳黴素的耐藥性，以及潮黴素和黴酚酸的耐藥性。BOSC23是癌症研究的模型，並且缺乏已活化的蛋白。
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BOSC 23 is a human kidney cell line developed by Warren Pear in David Baltimore's lab that was derived from the 293T cell line. The main use of BOSC 23 is the production of recombinant retroviruses; it stably expresses Moloney murine leukemia virus proteins and when transiently transfected with recombinant retroviral vector DNA, produces high titers of infectious retroviral particles. The cell line does not produce detectable replication-competent virus, an important safety feature. This cell line is a model for cancer research, with emphasis on the lack of activated Src protein.
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BOSC23
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BOSC23細胞
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26975239
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1107982814
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BOSC 23 is a human kidney cell line developed by Warren Pear in David Baltimore's lab that was derived from the 293T cell line. The main use of BOSC 23 is the production of recombinant retroviruses; it stably expresses Moloney murine leukemia virus proteins and when transiently transfected with recombinant retroviral vector DNA, produces high titers of infectious retroviral particles. The cell line does not produce detectable replication-competent virus, an important safety feature. BOSC 23 carries neomycin/G418 resistance derived from its parental line 293T, and also hygromycin and mycophenolic acid (gpt) resistance. It should be maintained under gpt selection. This cell line is a model for cancer research, with emphasis on the lack of activated Src protein.
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BOSC23是衍生自293T細胞系的人類腎細胞系，由沃倫·皮爾（Warren Pear）在戴維·巴爾的摩的實驗室中開發。BOSC23的主要用途是製造重組逆轉錄病毒。它穩定表達蛋白。當用重組反轉錄病毒載體DNA瞬時轉染時，會產生高滴度的感染性反轉錄病毒顆粒。該細胞不會產生具有複製能力的病毒，這是一項重要的安全功能。BOSC23具有源自其親本系293T的新黴素/ 遺傳黴素的耐藥性，以及潮黴素和黴酚酸的耐藥性。BOSC23是癌症研究的模型，並且缺乏已活化的蛋白。
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1848