Asfotase alfa

http://dbpedia.org/resource/Asfotase_alfa an entity of type: Thing

Asfotase alfa, sold under the brand name Strensiq, is a medication used in the treatment of people with perinatal/infantile- and juvenile-onset hypophosphatasia. The most common side effects include injection site reactions, hypersensitivity reactions (such as difficulty breathing, nausea, dizziness and fever), lipodystrophy (a loss of fat tissue resulting in an indentation in the skin or a thickening of fat tissue resulting in a lump under the skin) at the injection site, and ectopic calcifications of the eyes and kidney. rdf:langString
rdf:langString Asfotase alfa
xsd:integer 50368559
xsd:integer 1124060721
rdf:langString AB13
rdf:langString A16
xsd:integer 46
xsd:integer 7108
xsd:integer 1174277
xsd:integer 2108311
rdf:langString None
rdf:langString DB09105
<second> 432000.0
xsd:integer 11008
rdf:langString D10595
rdf:langString Rx-only
rdf:langString POM
rdf:langString Rx-only
xsd:integer 1968
xsd:integer 2206
xsd:integer 56
rdf:langString ALXN-1215
rdf:langString Strensiq
rdf:langString Z633861EIM
rdf:langString Asfotase alfa, sold under the brand name Strensiq, is a medication used in the treatment of people with perinatal/infantile- and juvenile-onset hypophosphatasia. The most common side effects include injection site reactions, hypersensitivity reactions (such as difficulty breathing, nausea, dizziness and fever), lipodystrophy (a loss of fat tissue resulting in an indentation in the skin or a thickening of fat tissue resulting in a lump under the skin) at the injection site, and ectopic calcifications of the eyes and kidney. The enzyme tissue non-specific alkaline phosphatase (ALP) plays a key role in creating and maintaining healthy bones, and managing calcium and phosphate in the body. People with hypophosphatasia cannot make enough working ALP, which leads to weak bones. Asfotase alfa is a version of the human ALP enzyme and serves as a replacement, thereby increasing levels of working ALP.
rdf:langString Asfotase_alfa
rdf:langString S4
rdf:langString Rx-only
rdf:langString yes
rdf:langString C
xsd:float 46.0
xsd:nonNegativeInteger 13249
rdf:langString Strensiq
xsd:string 1174277-80-5
xsd:string 2108311
xsd:string DB09105
xsd:string Z633861EIM
xsd:string D10595

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