Arfendazam
http://dbpedia.org/resource/Arfendazam an entity of type: Thing
L'arfendazam est une benzodiazépine 1,5 proche du clobazam. L'arfendazam est métabolisée en partie en clobazam. Elle a des propriétés principalement anxiolytiques, mais contrairement aux autres benzodiazépines, il s'agit d'un agoniste partiel des récepteurs GABAA, ce qui fait que les autres propriétés inhérentes aux benzodiazépines — anticonvulsivant, myorelaxant et amnésiant — sont moins marquées.
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L'arfendazam è uno psicofarmaco appartenente alla categoria delle benzodiazepine. Esso è una 1,5-benzodiazepina, con gli atomi di azoto situati nelle posizioni 1 e 5 dell'anello benzodiazepinico, e quindi è più strettamente correlata ad altre 1,5-benzodiazepine come il clobazam.
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Arfendazam (INN) is a drug which is a benzodiazepine derivative. Arfendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring, and so is most closely related to other 1,5-benzodiazepines such as clobazam. Arfendazam has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is a partial agonist at GABAA receptors, so the sedative effects are relatively mild and it produces muscle relaxant effects only at very high doses.
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Arfendazam
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Arfendazam
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Arfendazam
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Ethyl 7-chloro-4-oxo-5-phenyl-2,3-dihydro-1,5-benzodiazepine-1-carboxylate
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Arfendazam (INN) is a drug which is a benzodiazepine derivative. Arfendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring, and so is most closely related to other 1,5-benzodiazepines such as clobazam. Arfendazam has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is a partial agonist at GABAA receptors, so the sedative effects are relatively mild and it produces muscle relaxant effects only at very high doses. Arfendazam produces an active metabolite lofendazam, which is thought to be responsible for part of its effects.
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L'arfendazam est une benzodiazépine 1,5 proche du clobazam. L'arfendazam est métabolisée en partie en clobazam. Elle a des propriétés principalement anxiolytiques, mais contrairement aux autres benzodiazépines, il s'agit d'un agoniste partiel des récepteurs GABAA, ce qui fait que les autres propriétés inhérentes aux benzodiazépines — anticonvulsivant, myorelaxant et amnésiant — sont moins marquées.
rdf:langString
L'arfendazam è uno psicofarmaco appartenente alla categoria delle benzodiazepine. Esso è una 1,5-benzodiazepina, con gli atomi di azoto situati nelle posizioni 1 e 5 dell'anello benzodiazepinico, e quindi è più strettamente correlata ad altre 1,5-benzodiazepine come il clobazam.
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