Aldehyde tag
http://dbpedia.org/resource/Aldehyde_tag an entity of type: Person
Ein Aldehyd-Tag ist ein Protein-Tag mit einer Aldehydgruppe, das in der Biochemie zur Proteincharakterisierung verwendet wird.
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The aldehyde tag is a short peptide tag that can be further modified to add fluorophores, glycans, PEG (polyethylene glycol) chains or reactive groups for further synthesis. A short, genetically-encoded peptide, with a consensus sequence LCxPxR, is introduced into fusion proteins, and by subsequent treatment with the formylglycine-generating enzyme (FGE), the cysteine of the tag is converted to a reactive aldehyde group. This electrophilic group can be targeted by an array of aldehyde-specific reagents, such as aminooxy- or hydrazide-functionalized compounds.
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Aldehyd-Tag
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Aldehyde tag
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44764475
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1120570826
rdf:langString
Ein Aldehyd-Tag ist ein Protein-Tag mit einer Aldehydgruppe, das in der Biochemie zur Proteincharakterisierung verwendet wird.
rdf:langString
The aldehyde tag is a short peptide tag that can be further modified to add fluorophores, glycans, PEG (polyethylene glycol) chains or reactive groups for further synthesis. A short, genetically-encoded peptide, with a consensus sequence LCxPxR, is introduced into fusion proteins, and by subsequent treatment with the formylglycine-generating enzyme (FGE), the cysteine of the tag is converted to a reactive aldehyde group. This electrophilic group can be targeted by an array of aldehyde-specific reagents, such as aminooxy- or hydrazide-functionalized compounds.
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23028
