Adenovirus infection

rdf:langString Adenovirus infection

rdf:langString Adenovirus infection

rdf:langString Adenovirus infection

rdf:langString Signs and symptoms, PCR test

rdf:langString

rdf:langString B97.0

rdf:langString D000257

rdf:langString *Upper respiratory: nasal congestion, coryza, cough, wheeze, fast breathing sometimes no symptoms *General: fever, tiredness, chills, muscle aches, headache, tummy ache, tonsillitis, lymphadenopathy *Pharyngoconjunctival fever: pinky-red eyes, fever, sore throat *Keratoconjunctivitis: red painful eye, poor vision, intolerance to light, watery eyes, discharge, swelling of the conjunctiva *Gastroenteritis: diarrhoea, vomiting, tummy ache, *Urinary tract infection: Burning and increase frequency of passing urine

rdf:langString Symptomatic and supportive

rdf:langString Adenoviruses

rdf:langString Common, all ages, typically children under 5-years

rdf:langString Adenovirus infection is a contagious viral disease, caused by Adenoviruses, commonly resulting in a respiratory tract infection. Typical symptoms range from those of a common cold, such as nasal congestion, coryza and cough, to difficulty breathing as in pneumonia. Other general symptoms include fever, fatigue, muscle aches, headache, abdominal pain and swollen neck glands. Onset is usually two to fourteen days after exposure to the virus. A mild eye infection may occur on its own, combined with a sore throat and fever, or as a more severe adenoviral keratoconjunctivitis with a painful red eye, intolerance to light and discharge. Very young children may just have an earache. Adenovirus infection can present as a gastroenteritis with vomiting, diarrhoea and abdominal pain, with or without respiratory symptoms. However, some people have no symptoms. Adenovirus infection in humans are generally caused by Adenoviruses types B, C, E and F. Spread occurs mainly when an infected person is in close contact with another person. This may occur by either fecal–oral route, airborne transmission or small droplets containing the virus. Less commonly, the virus may spread via contaminated surfaces. Other respiratory complications include acute bronchitis, bronchiolitis and acute respiratory distress syndrome. It may cause myocarditis, meningoencephalitis or hepatitis in people with weak immune systems. Diagnosis is by signs and symptoms, and a laboratory test is not usually required. In some circumstances, a PCR test on blood or respiratory secretions may detect adenovirus DNA. Other conditions that appear similar include whooping cough, influenza, parainfluenza, and respiratory syncytial virus. Adenovirus gastroenteritis appears similar to diarrhoeal diseases caused by other infections. Infection by adenovirus may be prevented by washing hands, avoiding touching own eyes, mouth and nose with unwashed hands, and avoiding being near sick people. A live vaccine to protect against types 4 and 7 adenoviruses has been used successfully in some military personnel. Management is generally symptomatic and supportive. Most adenovirus infections get better without any treatment. Medicines to ease pain and reduce fever can be bought over the counter. Adenovirus infections affect all ages. They occur sporadically throughout the year, and outbreaks can occur particularly in winter and spring, when they may spread more quickly in closed populations such as in hospitals, nurseries, long-term care facilities, schools, and swimming pools. Severe disease is rare in people who are otherwise healthy. Adenovirus infection accounts for up to 10% of respiratory infections in children. Most cases are mild and by the age of 10-years, most children have had at least one adenovirus infection. 75% of conjunctivitis cases are due to adenovirus infection. In 2016, the Global Burden of Disease Study estimated that globally, around 75 million episodes of diarrhea among children under the age of five-years, were attributable to adenovirus infection. The first adenoviral strains were isolated in 1953 by Rowe et al.

rdf:langString *Respiratory: pneumonia, acute respiratory distress syndrome, bronchiolitis, acute bronchitis *Brain: meningoencephalitis *Heart: myocarditis, cardiomyopathy, pericarditis *Liver: hepatitis, liver disease *Kidney: nephritis

rdf:langString Washing hands, social distancing, avoid touching eyes, nose and mouth

rdf:langString Usually recover without treatment