AT-121

http://dbpedia.org/resource/AT-121 an entity of type: Thing

AT-121 is an experimental analgesic. It was designed to be bifunctional, acting as an agonist at both the μ-opioid receptor and the nociceptin receptor. The interaction with the nociceptin receptor is expected to block the abuse and dependence-related side effects that are typical of opioids. A study in nonhuman primates found that AT-121 has morphine-like analgesic effects, but suppressed the addictive effects. rdf:langString

rdfs:label

rdf:langString AT-121

dbpedia-owl:wikiPageID

xsd:integer 58386721

dbpedia-owl:wikiPageRevisionID

xsd:integer 1082989748

dbpprop:c

xsd:integer 24

dbpprop:casNumber

xsd:integer 2099681

dbpprop:h

xsd:integer 38

dbpprop:iupacName

xsd:integer 3

dbpprop:legalStatus

rdf:langString Investigational

dbpprop:n

xsd:integer 4

dbpprop:o

xsd:integer 3

dbpprop:pubchem

xsd:integer 129188444

dbpprop:s

xsd:integer 1

dbpprop:smiles

rdf:langString CC[C@H]1CC[C@H]N1CCC2CNCC1=CC=CC=C21

dbpedia-owl:abstract

rdf:langString AT-121 is an experimental analgesic. It was designed to be bifunctional, acting as an agonist at both the μ-opioid receptor and the nociceptin receptor. The interaction with the nociceptin receptor is expected to block the abuse and dependence-related side effects that are typical of opioids. A study in nonhuman primates found that AT-121 has morphine-like analgesic effects, but suppressed the addictive effects.

dbpedia-owl:wikiPageLength

xsd:nonNegativeInteger 3606

dbpedia-owl:casNumber

xsd:string 2099681-31-7

dbpedia-owl:pubchem

xsd:string 129188444

rdf:type

owl:Thing

<http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject>

dbpedia-owl:ChemicalSubstance

<http://www.wikidata.org/entity/Q8386>

dbpedia-owl:Drug