AC927
http://dbpedia.org/resource/AC927 an entity of type: Thing
AC927 or 1-(2-phenylethyl)piperidine is a selective sigma receptor antagonist, with reported binding affinity of Ki = 30 ± 2 nM for the sigma-1 receptor and Ki = 138 ± 18 nM for the sigma-2 receptor, and negligible binding affinity for other major central nervous system receptors, transporters, and ion channels. AC927 is reported to attenuate the locomotor stimulation induced by methamphetamine in mice.
rdf:langString
rdf:langString
AC927
xsd:integer
36157059
xsd:integer
1107939439
xsd:integer
13
xsd:integer
332
xsd:integer
9141
xsd:integer
19
xsd:integer
1
xsd:integer
1
xsd:integer
5
rdf:langString
AC927 or 1-(2-phenylethyl)piperidine is a selective sigma receptor antagonist, with reported binding affinity of Ki = 30 ± 2 nM for the sigma-1 receptor and Ki = 138 ± 18 nM for the sigma-2 receptor, and negligible binding affinity for other major central nervous system receptors, transporters, and ion channels. AC927 is reported to attenuate the locomotor stimulation induced by methamphetamine in mice.
xsd:nonNegativeInteger
2100
xsd:string
332-14-9
xsd:string
5TY7C52M7F