3CLpro-1

http://dbpedia.org/resource/3CLpro-1 an entity of type: Thing

3CLpro-1 is an antiviral drug related to rupintrivir which acts as a 3CL protease inhibitor and was originally developed for the treatment of human enterovirus 71. It is one of the most potent of a large series of compounds developed as inhibitors of the viral enzyme 3CL protease, with an in vitro IC50 of 200 nM. It also shows activity against coronavirus diseases such as SARS and MERS, and is under investigation as a potential treatment agent for the viral disease COVID-19. rdf:langString
3CLpro-1是一种与芦平曲韦相关的抗病毒药物,作为3C样蛋白酶抑制剂,最初开发用于治疗人类肠病毒71型。它是作为病毒酶3C样蛋白酶抑制剂开发的众多化合物中最有效的一种蛋白酶,体外为200nM。它还显示出对SARS和MERS等冠状病毒疾病的活性,并且正在研究作为病毒性疾病COVID-19的潜在治疗剂。病毒性疾病COVID-19的治疗剂。 rdf:langString
rdf:langString 3CLpro-1
rdf:langString 3CLpro-1
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rdf:langString Investigational drug
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xsd:integer 44578386
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rdf:langString 3CLpro-1 is an antiviral drug related to rupintrivir which acts as a 3CL protease inhibitor and was originally developed for the treatment of human enterovirus 71. It is one of the most potent of a large series of compounds developed as inhibitors of the viral enzyme 3CL protease, with an in vitro IC50 of 200 nM. It also shows activity against coronavirus diseases such as SARS and MERS, and is under investigation as a potential treatment agent for the viral disease COVID-19.
rdf:langString 3CLpro-1是一种与芦平曲韦相关的抗病毒药物,作为3C样蛋白酶抑制剂,最初开发用于治疗人类肠病毒71型。它是作为病毒酶3C样蛋白酶抑制剂开发的众多化合物中最有效的一种蛋白酶,体外为200nM。它还显示出对SARS和MERS等冠状病毒疾病的活性,并且正在研究作为病毒性疾病COVID-19的潜在治疗剂。病毒性疾病COVID-19的治疗剂。
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rdf:langString 3CLpro-1
xsd:string 2409054-43-7
xsd:string 477164
xsd:string 44578386

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